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- 1From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedFew data are available regarding the reliability of fluorescence in-situ hybridization (FISH), especially for chromosomal deletions, in high-throughput settings using tissue microarrays (TMAs). We performed a...
- 2From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedIt is unclear to what extent the host-responses elicited by Beijing versus non-Beijing strains of Mycobacterium tuberculosis (MTB) contribute to the predominance of modern Beijing strains in Taiwan and some other Asian...
- 3From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedFamilial adenomatous polyposis (FAP) is often due to adenomatous polyposis coli (APC) gene germline mutations. Somatic APC defects are found in about 80% of colorectal cancers (CRCs) and adenomas. Rapamycin inhibits...
- 4From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedThe "mechanistic target of rapamycin" (mTOR) is a central controller of growth, proliferation and/or motility of various celltypes ranging from adipocytes to immune cells, thereby linking metabolism and immunity. mTOR...
- 5From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedObjectives: This study investigated the antimicrobial resistance of Escherichia coli and enterococci isolated from freeranging Tibetan pigs in Tibet, China, and analyzed the influence of free-ranging husbandry on...
- 6From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedIntroduction: Research on urban food environments emphasizes limited access to healthy food, with fewer large supermarkets and higher food prices. Many residents of Hartford, Connecticut, which is often considered a food...
- 7From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedDNA methylation is an important part of epigenetics. In this study, we examined the methylation state of two CpG islands in the promoter of the p16 gene in radiation-induced thymic lymphoma samples. The mRNA and protein...
- 8From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedThere is considerable evidence that influenza A virus (IAV) promotes adherence, colonization, and superinfection by S. pneumoniae (Spn) and contributes to the pathogenesis of otitis media (OM). The complement system is a...
- 9From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedEpigenetic modifications are important early events during carcinogenesis. In particular, hypermethylation of CpG islands in the promoter region of tumor suppressor genes is a well-known mechanism of gene silencing that...
- 10From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedPummelo cultivars are usually difficult to identify morphologically, especially when fruits are unavailable. The problem was addressed in this study with the use of two methods: high resolution melting analysis of SNPs...
- 11From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedObjectives: Various studies have investigated the prognostic value of C-MYC aberrations in diffuse large B-cell lymphoma (DLBCL). However, the role of C-MYC as an independent prognostic factor in clinical practice...
- 12From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedRecently, diffuse-large-B-cell lymphoma (DLBCL) associated with serum IgM monoclonal component (MC) has been shown to be a very poor prognostic subset although, detailed pathological and molecular data are still lacking....
- 13From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedIntroduction: Chronic respiratory diseases cause a significant health and economic burden around the world. In Canada, Aboriginal populations are at increased risk of asthma and chronic obstructive pulmonary disease...
- 14From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedAims: To determine the spectrum of renal lesions in patients with kidney involvement in non-Hodgkin's lymphoma (NHL) by renal biopsy. Methods: The clinical features and histological findings at the time of the renal...
- 15From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedAvian malaria is a mosquito-borne disease caused by Plasmodium spp. Avian plasmodia are recognized conservation- threatening pathogens due to their potential to cause severe epizootics when introduced to bird populations...
- 16From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedVarious adverse effects related to landfill leachate have made leachates an important issue in past decades, and it has been demonstrated that landfill leachate is an important source of environmental estrogens. In this...
- 17From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedObjective: In Malaysia, futsal is a popular sport played by individuals across all ages and genders. Despite its popularity, information on futsal related injury in Malaysia is not available. The purpose of this study is...
- 18From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedMantle cell lymphoma (MCL) is associated with a significant risk of therapeutic failure and disease relapse, but the biological origin of relapse is poorly understood. Here, we prospectively identify subpopulations of...
- 19From: PLoS ONE. (Vol. 9, Issue 4) Peer-ReviewedInterleukin-9 (IL-9) is more functionally diverse than previously expected, especially with regards to lymphomagenesis. However, the relationship between IL-9 and the clinicopathological features of extranodal NK/T-cell...
- 20From: PLoS ONE. (Vol. 9, Issue 4) Peer-Reviewed20-hydroxyeicosatetraenoic acid (20-HETE) induces endothelial dysfunction and is correlated with diabetes. This study was designed to investigate the effects of 20-HETE on endothelial insulin signaling.Human umbilical...