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- Search Terms:ISSN: 15537390AndISSN: 15537404AndVolume Number: 9AndIssue Number: 3AndStart Page: e1003383AndDate: 2013 Revise Search
- 1From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedThe phylogeographic population structure of Mycobacterium tuberculosis suggests local adaptation to sympatric human populations. We hypothesized that HIV infection, which induces immunodeficiency, will alter the...
- 2From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedDisturbance of cellular functions results in the activation of stress-signaling pathways that aim at restoring homeostasis. We performed a genome-wide screen to identify components of the signal transduction of the...
- 3From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedIn insects, products of the male reproductive tract are essential for initiating and maintaining the female post-mating response (PMR). The PMR includes changes in egg laying, receptivity to courting males, and sperm...
- 4From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedThe cohesion of sister chromatids in the interval between chromosome replication and anaphase is important for preventing the precocious separation, and hence nondisjunction, of chromatids. Cohesion is accomplished by a...
- 5From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedCentromeres are specialized chromatin regions marked by the presence of nucleosomes containing the centromere-specific histone H3 variant CENP-A, which is essential for chromosome segregation. Assembly and disassembly...
- 6From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedThe number of chromosome sets contained within the nucleus of eukaryotic organisms is a fundamental yet evolutionarily poorly characterized genetic variable of life. Here, we mapped the impact of ploidy on the mitotic...
- 7From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedA variety of extracellular factors regulate morphogenesis during development. However, coordination between extracellular signaling and dynamic morphogenesis is largely unexplored. We address the fundamental question by...
- 8From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedGonadal failure, along with early pregnancy loss and perinatal death, may be an important filter that limits the propagation of harmful mutations in the human population. We hypothesized that men with spermatogenic...
- 9From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedDuring development, tissue-specific transcription factors regulate both protein- coding and non-coding genes to control differentiation. Recent studies have established a dual role for the transcription factor Pax6 as...
- 10From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedCohesin is a well-known mediator of sister chromatid cohesion, but it also influences gene expression and development. These non-canonical roles of cohesin are not well understood, but are vital: gene expression and...
- 11From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedEssentially all biological processes depend on protein-protein interactions (PPIs). Timing of such interactions is crucial for regulatory function. Although circadian (~24-hour) clocks constitute fundamental cellular...
- 12From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedVoltage-gated ion channels are essential for electrical signaling in neurons and other excitable cells. Among them, voltage-gated sodium and calcium channels are four-domain proteins, and ion selectivity is strongly...
- 13From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedCereal endosperm represents 60% of the calories consumed by human beings worldwide. In addition, cereals also serve as the primary feedstock for livestock. However, the regulatory mechanism of cereal endosperm and seed...
- 14From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedRare variation in protein coding sequence is poorly captured by GWAS arrays and has been hypothesized to contribute to disease heritability. Using the Illumina HumanExome SNP array, we successfully genotyped 191,032...
- 15From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedGenome-wide association studies (GWAS) have identified ~100 loci associated with blood lipid levels, but much of the trait heritability remains unexplained, and at most loci the identities of the trait-influencing...
- 16From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedMany genetic variants that are significantly correlated to gene expression changes across human individuals have been identified, but the ability of these variants to predict expression of unseen individuals has rarely...
- 17From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedGenome rearrangements are associated with eukaryotic evolutionary processes ranging from tumorigenesis to speciation. Rearrangements are especially common following interspecific hybridization, and some of these could...
- 18From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedGene transfer agents (GTAs) randomly transfer short fragments of a bacterial genome. A novel putative GTA was recently discovered in the mouse-infecting bacterium Bartonella grahamii. Although GTAs are widespread in...
- 19From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedMicroRNAs (miRNAs), single-stranded non-coding RNAs, influence myriad biological processes that can contribute to cancer. Although tumor-suppressive and oncogenic functions have been characterized for some miRNAs, the...
- 20From: PLoS Genetics. (Vol. 9, Issue 3) Peer-ReviewedYes. In answer to your question, yes, this is an interview with the Southern, as in the eponymous blot. Devised in the mid-1970s, Southern's technique for transferring DNA from gels onto nitrocellulose paper allowed...