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- Search Terms:ISSN: 19352727AndISSN: 19352735AndVolume Number: 8AndIssue Number: 8AndStart Page: e3068AndDate: 2014 Revise Search
- 1From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedSporotrichosis associated with zoonotic transmission remains a relevant public health problem in Rio de Janeiro, Brazil, affecting a large at-risk population, which includes HIV-infected individuals. We assessed...
- 2From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedDengue, a vector-borne viral disease of increasing global importance, is classically associated with tropical and sub- tropical regions around the world. Urbanisation, globalization and climate trends, however, are...
- 3From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedBackground: With the paucity of new drugs and HIV co-infection, vaccination remains an unmet research priority to combat visceral leishmaniasis (VL) requiring strong cellular immunity. Protein vaccination often suffers...
- 4From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-Reviewed
Dissemination of Orientia tsutsugamushi and inflammatory responses in a murine model of scrub typhus
Central aspects in the pathogenesis of scrub typhus, an infection caused by Orientia (O.) tsutsugamushi, have remained obscure. Its organ and cellular tropism are poorly understood. The purpose of this study was to... - 5From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedIntroduction Soil-transmitted helminth (also known as "geohelminth") infections are among the most common chronic infections worldwide. The World Health Organization (WHO) estimates that almost 900 million children...
- 6From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedIntroduction: In 2005, Bangladesh, India, and Nepal joined forces to eliminate Visceral Leishmaniasis (or kala-azar) from the region by 2015. In Bangladesh the elimination target is set at less than one new case per...
- 7From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedBackground: Mucosal Associated Invariant T (MAIT) cells are innate-like T cells found in abundance in the intestinal mucosa, and are thought to play a role in bridging the innate-adaptive interface. Methods: We...
- 8From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedBackground: Visceral Leishmaniasis (VL;also known as kala-azar) is an ultimately fatal disease endemic in the Indian state of Bihar, while HIV/AIDS is an emerging disease in this region. A 2011 observational cohort...
- 9From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedBackground: Understanding the mechanisms that influence the population dynamics and spatial genetic structure of the vectors of pathogens infecting humans is a central issue in tropical epidemiology. In view of the...
- 10From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedToxocariasis is an important neglected tropical disease that can manifest as visceral or ocular larva migrans, or covert toxocariasis. All three forms pose a public health problem and cause significant morbidity in...
- 11From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedBackground: Snake bite causes greater mortality than most of the other neglected tropical diseases. Snake antivenom, although effective in minimizing mortality in developed countries, is not equally so in developing...
- 12From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedWhile bacterial symbionts influence a variety of host cellular responses throughout development, there are no documented instances in which symbionts influence early embryogenesis. Here we demonstrate that Wolbachia, an...
- 13From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedEmerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the...
- 14From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedBackground: Aedes albopictus is an invasive species which continues expanding its geographic range and involvement in mosquito-borne diseases such as chikungunya and dengue. Host selection patterns by invasive...
- 15From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedDengue virus host factors (DENV HFs) that are essential for the completion of the infection cycle in the mosquito vector and vertebrate host represent potent targets for transmission blocking. Here we investigated...
- 16From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedBuruli ulcer (BU) is a neglected tropical disease caused by Mycobacterium ulcerans. The tissue damage characteristic of BU lesions is known to be driven by the secretion of the potent lipidic exotoxin mycolactone....
- 17From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedBackground: Leishmaniasis is a parasitic disease associated with extensive mortality and morbidity. The treatment for leishmaniasis is currently based on pentavalent antimonials and amphotericin B; however, these drugs...
- 18From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedBackground: Paracoccidioides brasiliensis and P. lutzii cause paracoccidioidomycosis (PCM). P. brasiliensis main diagnostic antigen is glycoprotein gp43, and its peptide sequence is 81% identical with a P. lutzii...
- 19From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedEarly malacological literature suggests that the outbreak of schistosomiasis, a parasitic disease transmitted by aquatic snails, in the Senegal River basin occurred due to ecological changes resulting from the...
- 20From: PLoS Neglected Tropical Diseases. (Vol. 8, Issue 8) Peer-ReviewedBackground: Schistosomiasis and STH are among the list of neglected tropical diseases considered for control by the WHO. Although both diseases are endemic in Zimbabwe, no nationwide control interventions have been...