Showing Results for
- Academic Journals (67)
Search Results
- 67
Academic Journals
- 67
- Search Terms:ISSN: 15537366AndISSN: 15537374AndVolume Number: 8AndIssue Number: 8AndStart Page: e1002859AndDate: 2012 Revise Search
- 1From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedA highly conserved virulence plasmid encoding a type III secretion system is shared by the three Yersinia species most pathogenic for mammals. Although factors encoded on this plasmid enhance the ability of Yersinia to...
- 2From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedThe biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence structure, protecting bacteria from the host immune system and antimicrobial therapy. However,...
- 3From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedBK polyomavirus (BKPyV) is an emerging pathogen whose reactivation causes severe disease in transplant patients. Unfortunately, there is no specific anti-BKPyV treatment available, and host cell components that affect...
- 4From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedInvasive candidiasis is the 4th leading cause of nosocomial bloodstream infection in the US with mortality that exceeds 40% despite administration of antifungal therapy;neutropenia is a major risk factor for poor...
- 5From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedDuring retrovirus particle maturation, the assembled Gag polyprotein is cleaved by the viral protease into matrix (MA), capsid (CA), and nucleocapsid (NC) proteins. To form the mature viral capsid, CA rearranges,...
- 6From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedThe innate immune response mediated by cells such as natural killer (NK) cells is critical for the rapid containment of virus replication and spread during acute infection. Here, we show that subtype 11 of the type I...
- 7From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedWhat Are the Unique Challenges of Mammalian Gestation? Mammalian gestation creates an immunological paradox wherein the body must balance tolerance of an allogeneic fetus with protection against invading...
- 8From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedIL-10 is an anti-inflammatory cytokine that regulates the extent of host immunity to infection by exerting suppressive effects on different cell types. Herpes viruses induce IL-10 to modulate the virus-host balance...
- 9From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedLittle is known about the role of viral genes in modulating host cytokine responses. Here we report a new functional role of the viral encoded IE1 protein of the murine cytomegalovirus in sculpting the inflammatory...
- 10From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedPlants evoke innate immunity against microbial challenges upon recognition of pathogen-associated molecular patterns (PAMPs), such as fungal cell wall chitin. Nevertheless, pathogens may circumvent the host...
- 11From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedOxidative stress serves as an important host/environmental signal that triggers a wide range of responses in microorganisms. Here, we identified an oxidative stress sensor and response regulator in the important...
- 12From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedParamyxovirus hemagglutinin-neuraminidase (HN) plays roles in viral entry and maturation, including binding to sialic acid receptors, activation of the F protein to drive membrane fusion, and enabling virion release...
- 13From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedHepatitis C virus (HCV) is present in the host with multiple variants generated by its error prone RNA-dependent RNA polymerase. Little is known about the initial viral diversification and the viral life cycle processes...
- 14From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedUbiquitin, a highly conserved polypeptide of 76 amino acids, participates in a vast range of eukaryotic cell processes through its role as a reversible post-translational modifier (see review [1], Figure 1A). Such...
- 15From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedFungal septicemia is an increasingly common complication of immunocompromised patients worldwide. Candida species are the leading cause of invasive mycoses with Candida glabrata being the second most frequently isolated...
- 16From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedBacteria in the genus Chlamydia are major human pathogens that cause an intracellular infection. A chlamydial protease, CPAF, has been proposed as an important virulence factor that cleaves or degrades at least 16 host...
- 17From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedWolbachia are widespread endosymbionts found in a large variety of arthropods. While these bacteria are generally transmitted vertically and exhibit weak virulence in their native hosts, a growing number of studies...
- 18From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedLike cancer cells, virally infected cells have dramatically altered metabolic requirements. We analyzed global metabolic changes induced by latent infection with an oncogenic virus, Kaposi's Sarcoma-associated...
- 19From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedEmerging influenza viruses are a serious threat to human health because of their pandemic potential. A promising target for the development of novel anti-influenza therapeutics is the PA protein, whose endonuclease...
- 20From: PLoS Pathogens. (Vol. 8, Issue 8) Peer-ReviewedHuman bocavirus 1 (HBoV1) has been identified as one of the etiological agents of wheezing in young children with acute respiratory-tract infections. In this study, we have obtained the sequence of a full-length HBoV1...