Showing Results for
- Academic Journals (24)
Search Results
- 24
Academic Journals
- 24
- Search Terms:
- 1From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedMeningioma is a type of brain tumour that is known to exhibit some familial association, indicating that there might be genetic predisposition. In addition, exposure to ionizing radiation is also associated with an...
- 2From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedCorrect regulation of the process by which stem cells start differentiating is crucial to normal development and to the avoidance of cancer. Two new studies show the importance of specific microRNAs (miRNAs) in the...
- 3From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedMammals exhibit oscillations in metabolism, physiology and behaviour with a near 24 h periodicity, a phenomenon known as the circadian rhythm. Changes to circadian oscillations, or phases, are associated with an...
- 4From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedChang, S.-F. et al. Proc. Natl Acad. Sci. USA 105, 3927-3932 (2008) Interstitial fluid flow within and surrounding a tissue can affect the mechanical environment, which is characterized by shear stress, pressure forces...
- 5From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedIn any good relay race, the baton needs to be passed from one competent team member to the next. For the past 6 years Nature Reviews Cancer has been under the leadership of Ezzie Hutchinson, and in that time the journal...
- 6From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedWhen a tumour cell becomes metastatic it acquires many new abilities, such as motility, invasiveness and survival in the circulation; these are associated with a dramatically different gene expression profile. How do...
- 7From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedCancers that arise as a result of mutation in either BRCA1 or BRCA2 are deficient in specific aspects of DNA repair and are sensitive to drugs that exploit this weakness, unless resistance occurs. Two groups have now...
- 8From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedThe use of mammography screening has significantly increased the frequency of diagnosis of ductal carcinoma in situ (DCIS). This type of breast cancer has a relatively good overall prognosis, whereby the local recurrence...
- 9From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedAbstract | GATA1 is a prototypical lineage-restricted transcription factor that is central to the correct differentiation, proliferation and apoptosis of erythroid and megakaryocytic cells. Mutations in GATA1 can...
- 10From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedThe Drosophila melanogaster Salvador (SAV)--Warts (WTS)--Hippo (HPO) pathway is a conserved tumour suppressor pathway that functions to regulate cell growth and apoptosis through inhibition of the downstream...
- 11From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedAbstract | The importance of multidisciplinary translational clinical trials is obvious; however, making them work is complex and challenging. Here I present an argument for designing and implementing multidisciplinary...
- 12From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedYi, P. et al. Mol. Cell 29, 465-476 (2008) Nuclear receeptor coactivator 3 (NCOA3; also known as SRC-3 and AIB1) is a steroid receptor co-activator that is amplified and overexpressed in a number of cancers, including...
- 13From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedAbstract | Testing for prostate-specific antigen (PSA) has profoundly affected the diagnosis and treatment of prostate cancer. PSA testing has enabled physicians to detect prostate tumours while they are still small,...
- 14From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedSince its discovery, BCL2 has been viewed as a mild-mannered oncogene--tumorigenic over a protracted time course in comparison with seasoned professionals such as MYC and KRAS. However, over recent years evidence has...
- 15From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedIt was Otto Warburg who first noted the difference between metabolism in cancer cells and that in normal adult tissues: cancer cells take up glucose at higher rates than normal tissue but use a smaller fraction of this...
- 16From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedKatajisto, P. et al. Nature Genet. 2 Mar 2008 (doi 10.1038/ng.98) Germline mutations in STK11, the gene encoding the tumour suppressor LKB1, are present in patients with Peutz-Jeghers syndrome (PJS). Pekka Katajisto...
- 17From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedFiona M. Watt, Michaela Frye and Salvador Aznar Benitah Nature Reviews Cancer 8, 234-242 (2008) The author affiliation for Salvador Aznar Benitah on page 241 was incorrect. The correct affiliation is shown below. ICREA...
- 18From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedRadiation therapy can be followed by recurrence because a small population of cancer stem cells is resistant to the therapy. A new study shows that radiation therapy causes apoptosis in proliferating medulloblastoma...
- 19From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedAbstract | One explanation for the relative lack of progress in treating cancer in adolescents and young adults is that the biology of malignant diseases in this age group is different than in younger and older persons,...
- 20From: Nature Reviews Cancer. (Vol. 8, Issue 4) Peer-ReviewedAbstract | The cyclin-dependent kinase (Cdk) inhibitor p27 (also known as KIP1) regulates cell proliferation, cell motility and apoptosis. Interestingly, the protein can exert both positive and negative functions on...