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- Search Terms:ISSN: 15537366AndISSN: 15537374AndVolume Number: 8AndIssue Number: 3AndStart Page: e1002611AndDate: 2012 Revise Search
- 1From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedIdentifying naturally-occurring neutralizing antibodies (NAb) that are cross-reactive against all global subtypes of HIV-1 is an important step toward the development of a vaccine. Establishing the host and viral...
- 2From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedBrucella are facultative intracellular bacteria that chronically infect humans and animals causing brucellosis. Brucella are able to invade and replicate in a broad range of cell lines in vitro, however the cells...
- 3From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedVibrio parahaemolyticus is a leading cause of seafood-borne gastroenteritis in many parts of the world, but there is limited knowledge of the pathogenesis of V. parahaemolyticus-induced diarrhea. The absence of an oral...
- 4From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedWhile influenza viruses are a common respiratory pathogen, sporadic reports of conjunctivitis following human infection demonstrates the ability of this virus to cause disease outside of the respiratory tract. The...
- 5From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-Reviewed
Visualization and measurement of ATP levels in living cells replicating hepatitis C virus genome RNA
Adenosine 5'-triphosphate (ATP) is the primary energy currency of all living organisms and participates in a variety of cellular processes. Although ATP requirements during viral lifecycles have been examined in a... - 6From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedThe human pathogen Haemophilus influenzae has the ability to quickly adapt to different host environments through phase variation of multiple structures on its lipooligosaccharide (LPS), including phosphorylcholine...
- 7From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedBotulism, characterized by flaccid paralysis, commonly results from botulinum neurotoxin (BoNT) absorption across the epithelial barrier from the digestive tract and then dissemination through the blood circulation to...
- 8From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedVaccination is highly effective in preventing various infectious diseases, whereas the constant threat of new emerging pathogens necessitates the development of innovative vaccination principles that also confer rapid...
- 9From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedTetherin is a membrane protein of unusual topology expressed from rodents to humans that accumulates enveloped virus particles on the surface of infected cells. However, whether this 'tethering' activity promotes or...
- 10From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedThe female Aedes aegypti salivary gland plays a pivotal role in bloodmeal acquisition and reproduction, and thereby dengue virus (DENV) transmission. It produces numerous immune factors, as well as immune-modulatory,...
- 11From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedCandida albicans is a major life-threatening human fungal pathogen. Host defence against systemic Candida infection relies mainly on phagocytosis of fungal cells by cells of the innate immune system. In this study, we...
- 12From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedCerebral malaria is a major, life-threatening complication of Plasmodium falciparum malaria, and has very high mortality rate. In murine malaria models, natural killer (NK) cell responses have been shown to play a...
- 13From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedIntroduction Intracellular pathogens are a major cause of global morbidity and mortality. While this alone establishes their medical importance, they are also a focus of special interest because of their unique...
- 14From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-Reviewed4-anilino quinazolines have been identified as inhibitors of HCV replication. The target of this class of compounds was proposed to be the viral protein NS5A, although unequivocal proof has never been presented. A...
- 15From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedTranslation is a regulated process and is pivotal to proper cell growth and homeostasis. All retroviruses rely on the host translational machinery for viral protein synthesis and thus may be susceptible to its...
- 16From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedThe mechanism underlying persistent hepatitis B virus (HBV) infection remains unclear. We investigated the role of innate immune responses to persistent HBV infection in 154 HBV-infected patients and 95 healthy...
- 17From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedThe HIV-1 accessory protein Vpu counteracts tetherin (BST-2/CD317) by preventing its incorporation into virions, reducing its surface expression, and ultimately promoting its degradation. Here we characterize a putative...
- 18From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedVirus-like particles (VLPs) have not been observed in Caenorhabditis germ cells, although nematode genomes contain low numbers of retrotransposon and retroviral sequences. We used electron microscopy to search for VLPs...
- 19From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedThe influenza virus uses the hemagglutinin (HA) and neuraminidase (NA) glycoproteins to interact with and infect host cells. While biochemical and microscopic methods allow examination of the early steps in flu...
- 20From: PLoS Pathogens. (Vol. 8, Issue 3) Peer-ReviewedWhat Are Blastocystis spp.? Blastocystis spp. belong to the phylum Stramenopila, a complex and heterogeneous evolutionary assemblage of heterotrophic and photosynthetic protozoa [1]. Interestingly, this is the only...