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- Search Terms:ISSN: 15537366AndISSN: 15537374AndVolume Number: 8AndIssue Number: 10AndStart Page: e1002978AndDate: 2012 Revise Search
- 1From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedGastric cancer development is strongly correlated with infection by Helicobacter pylori possessing the effector protein CagA. Using a transgenic Drosophila melanogaster model, we show that CagA expression in the simple...
- 2From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedToxin-antitoxin (TA) systems are prevalent in many bacterial genomes and have been implicated in biofilm and persister cell formation, but the contribution of individual chromosomally encoded TA systems during bacterial...
- 3From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedDuring antagonistic coevolution between viruses and their hosts, viruses have a major advantage by evolving more rapidly. Nevertheless, viruses and their hosts coexist and have coevolved, although the processes remain...
- 4From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedHuman Cytomegalovirus (HCMV) is a ubiquitous herpesvirus that currently infects a large percentage of the world population. Although usually asymptomatic in healthy individuals, HCMV infection during pregnancy may cause...
- 5From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedMolecular genetic approaches typically detect recombination in microbes regardless of assumed asexuality. However, genetic data have shown the AIDS-associated pathogen Penicillium marneffei to have extensive spatial...
- 6From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedSchistosomes, parasitic flatworms that cause the neglected tropical disease schistosomiasis, have been considered to have an entirely carbohydrate based metabolism, with glycolysis playing a dominant role in the adult...
- 7From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedKlebsiella (K.) pneumoniae is a common cause of pneumonia-derived sepsis. Myeloid related protein 8 (MRP8, S100A8) and MRP14 (S100A9) are the most abundant cytoplasmic proteins in neutrophils. They can form MRP8/14...
- 8From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedWe have investigated the potential of the GTP synthesis pathways as chemotherapeutic targets in the human pathogen Cryptococcus neoformans, a common cause of fatal fungal meningoencephalitis. We find that de novo GTP...
- 9From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedSepsis is a frequent complication in critical illness. The mechanisms that are involved in initiation and propagation of the disease are not well understood. Scavenger receptor A (SRA) is a membrane receptor that binds...
- 10From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedDengue virus (DENV) is a pathogen with a high impact on human health. It replicates in a wide range of cells involved in the immune response. To efficiently infect humans, DENV must evade or inhibit fundamental elements...
- 11From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedHashimoto's thyroiditis (HT) is the most common of all thyroid diseases and is characterized by abundant lymphocyte infiltrate and thyroid impairment, caused by various cell- and antibody-mediated immune processes....
- 12From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedPest and pathogen losses jeopardise global food security and ever since the 19th century Irish famine, potato late blight has exemplified this threat. The causal oomycete pathogen, Phytophthora infestans, undergoes...
- 13From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedThe dynamics of reductive genome evolution for eukaryotes living inside other eukaryotic cells are poorly understood compared to well-studied model systems involving obligate intracellular bacteria. Here we present 8.5...
- 14From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedIntroduction Extra-intestinal E. coli (ExPEC) may transition from benign colonization of the enteric and vaginal tracts to cause urinary tract infections (UTIs), septicemia, and meningitis. ExPEC colonization of the...
- 15From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedTwo gammaherpesviruses, Epstein-Barr virus (EBV) (Lymphocryptovirus genus) and Kaposi's sarcoma-associated herpesvirus (KSHV) (Rhadinovirus genus) have been implicated in the etiology of AIDS-associated lymphomas....
- 16From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedMalaria transmission requires the production of male and female gametocytes in the human host followed by fertilization and sporogonic development in the mosquito midgut. Although essential for the spread of malaria...
- 17From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedThe serine-rich repeat glycoprotein Srr1 of Streptococcus agalactiae (GBS) is thought to be an important adhesin for the pathogenesis of meningitis. Although expression of Srr1 is associated with increased binding to...
- 18From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedNeisseria meningitis remains a leading cause of sepsis and meningitis, and vaccines are required to prevent infections by this important human pathogen. Factor H binding protein (fHbp) is a key antigen that elicits...
- 19From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedOwing to the capricious political and economic conditions of Afghanistan during the past few decades, the burden of communicable disease, especially blood-borne and sexually transmitted infections, has been steadily...
- 20From: PLoS Pathogens. (Vol. 8, Issue 10) Peer-ReviewedRabies virus (RABV) is a highly neurotropic pathogen that typically leads to mortality of infected animals and humans. The precise etiology of rabies neuropathogenesis is unknown, though it is hypothesized to be due...