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- 1From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Vanessa Tillement [1]; Laurence Haren [1]; Nicolas Roullet [1]; Chantal Etievant [1]; Andreas Merdes (corresponding author) [1] Background The centrosome is a cellular structure responsible for the...
- 2From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Rolf I Skotheim (corresponding author) [1,2]; Gard OS Thomassen [1,2,3]; Marthe Eken [1,2,4]; Guro E Lind [1,2]; Francesca Micci [5]; Franclim R Ribeiro [1,2,6]; Nuno Cerveira [6]; Manuel R Teixeira [2,6];...
- 3From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Giulia Matusali [1]; Giuseppe Arena [1]; Alessandra De Leo [1]; Livia Di Renzo [2]; Elena Mattia (corresponding author) [1] Background Epstein Barr Virus (EBV), the causative agent of infectious...
- 4From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Tae-Yeon Eom; Richard S Jope (corresponding author) [1,2] Findings Glycogen synthase kinase-3 (GSK3) phosphorylates more than 40 substrates, so its actions must be controlled in a substrate-specific manner...
- 5From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Jing Li [1]; Brandon Orr [1]; Kayla White [1]; Natalia Belogortseva [1]; Richard Niles [1]; Goran Boskovic [2]; Hanh Nguyen [1]; Ava Dykes [3]; Maiyon Park (corresponding author) [1] Background Retinoids are...
- 6From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Yan Zeng [1]; Agustin Abdallah [1]; Jian-Ping Lu [1]; Tao Wang [1,3]; Yan-Hua Chen [1,2]; David M Terrian [1,2]; Kwonseop Kim [1,4]; Qun Lu (corresponding author) [1,2] Background Tumor progression is the...
- 7From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Therese M Becker (corresponding author) [1]; Sebastian Haferkamp [1]; Menno K Dijkstra [1]; Lyndee L Scurr [1]; Monika Frausto [1]; Eve Diefenbach [2]; Richard A Scolyer [3]; David N Reisman [4]; Graham J Mann...
- 8From: Molecular Cancer. (Vol. 8) Peer-Reviewed
CHK1 inhibition as a strategy for targeting fanconi anemia (FA) DNA repair pathway deficient tumors.
Authors: Clark C Chen (equal contributor) [1,2]; Richard D Kennedy (equal contributor) [1]; Samuel Sidi [3]; A Thomas Look [3]; Alan D'Andrea (corresponding author) [1] Background Human cancers exhibit genomic... - 9From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Martin Wilson (corresponding author) [1,2]; Nigel P Davies [1,2,3]; Marie-Anne Brundler [2]; Carmel McConville [1,2]; Richard G Grundy [4]; Andrew C Peet (corresponding author) [1,2] Background Childhood...
- 10From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Matilde E LLeonart (corresponding author) [1]; Ana Artero-Castro [1]; Hiroshi Kondoh (corresponding author) [2] Background Primary mammalian cells reach proliferative exhaustion after serial passage in...
- 11From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Androu Arsanious [1]; Georg A Bjarnason [2]; George M Yousef (corresponding author) [1,3] Renal cell carcinoma: A clinical overview The American Cancer Society predicts that there will be about 54,000 new...
- 12From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Samy L Habib (corresponding author) [1,2] Background Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder associated with tumors in many organs, particularly angiomyolipoma in the...
- 13From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: György Stuber [1]; Emilie Flaberg [1,2,3]; Gabor Petranyi [1,2,4]; Rita Ãtvös [1]; Nina Rökaeus [5]; Elena Kashuba [1,3]; Klas G Wiman [5]; George Klein [1]; Laszlo Szekely (corresponding author) [1,2,3]...
- 14From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Keqiang Zhang [1]; Shuya Hu [1]; Jun Wu [1]; Linling Chen [1]; Jianming Lu [2]; Xiaochen Wang [1]; Xiyong Liu [1]; Bingsen Zhou [1]; Yun Yen (corresponding author) [1] Background Ribonucleotide reductase...
- 15From: Molecular Cancer. (Vol. 8) Peer-ReviewedBackground Previously we have shown that B cell receptor (BCR) expression and B cell receptor signaling pathways are important for the basal growth of B lymphoma cells. In particular we have shown that the activation...
- 16From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Lavinia Nardinocchi [1]; Rosa Puca [1]; Ada Sacchi [1]; Gabriella D'Orazi (corresponding author) [1,2] Background Homeodomain-interacting protein kinase-2 (HIPK2) is a serine/threonine kinase [1] that as...
- 17From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Joshua P Klopper (corresponding author) [1,2]; Vibha Sharma [1]; Andrew Berenz [1]; William R Hays [1]; Michele Loi [1]; Umarani Pugazhenthi [1]; Sherif Said [3]; Bryan R Haugen [1,2] Background Melanoma...
- 18From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Michael A Gorin [1]; Quintin Pan (corresponding author) [2,3] Introduction to the protein kinase C (PKC) family Several decades of research have documented that members of the protein kinase C (PKC) family...
- 19From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Maider Zabala [1,4]; Pilar Alzuguren [1]; Carolina Benavides [2]; Julien Crettaz [1]; Gloria Gonzalez-Aseguinolaza [1]; Carlos Ortiz de Solorzano [2]; Manuela Gonzalez-Aparicio [1]; Maria Gabriela Kramer [1,5];...
- 20From: Molecular Cancer. (Vol. 8) Peer-ReviewedAuthors: Amara C Siva [1]; Luke J Nelson [1]; Chad L Fleischer [1]; Mehrdad Majlessi [1]; Michael M Becker [1]; Robert L Vessella [2,3]; Mark A Reynolds (corresponding author) [1] Background MicroRNAs (miRNAs) are...