Showing Results for
- Academic Journals (37)
Search Results
- 37
Academic Journals
- 37
- Search Terms:
- 1From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedPromyelocytic leukemia protein (PML) has antiviral functions and many viruses encode gene products that disrupt PML nuclear bodies (PML NBs). However, evidence of the relevance of PML NB modification for viral...
- 2From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedRhodococcus equi causes fatal pyogranulomatous pneumonia in foals and immunocompromised animals and humans. Despite its importance, there is currently no effective vaccine against the disease. The actinobacteria R. equi...
- 3From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedWhile the exopolysaccharide component of the biofilm matrix has been intensively studied, much less is known about matrix-associated proteins. To better understand the role of these proteins, we undertook a proteomic...
- 4From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedFacultative bacterial pathogens must adapt to multiple stimuli to persist in the environment or establish infection within a host. Temperature is often utilized as a signal to control expression of virulence genes...
- 5From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedThe genus Salmonella contains two species, S. bongori and S. enterica. Compared to the well-studied S. enterica there is a marked lack of information regarding the genetic makeup and diversity of S. bongori. S. bongori...
- 6From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedNatural killer (NK) cells are an important element in the immune defense against the orthopox family members vaccinia virus (VV) and ectromelia virus (ECTV). NK cells are regulated through inhibitory and activating...
- 7From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedRegulatory T cells (Treg) diminish immune responses to microbial infection, which may contribute to preventing inflammation-related local tissue damage and autoimmunity but may also contribute to chronicity of...
- 8From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedMany viruses attach to target cells by binding to cell-surface glycans. To gain a better understanding of strategies used by viruses to engage carbohydrate receptors, we determined the crystal structures of reovirus...
- 9From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedNecrotrophic fungi are unable to occupy living plant cells. How such pathogens survive first contact with living host tissue and initiate infection is therefore unclear. Here, we show that the necrotrophic grey mold...
- 10From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedSeveral extensive small molecule screens against growing Plasmodium falciparum have recently been published [1-3] and thousands of hit structures are now publicly available. This represents a large majority of the...
- 11From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedThe building blocks of bacterial flagella, flagellin monomers, are potent stimulators of host innate immune systems. Recognition of flagellin monomers occurs by flagellin-specific pattern-recognition receptors, such as...
- 12From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedIn eukaryotic cells, the unfolded protein response (UPR) pathway plays a crucial role in cellular homeostasis of the endoplasmic reticulum (ER) during exposure to diverse environmental conditions that cause ER stress....
- 13From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedRecently, genome sequencing of many isolates of genetically monomorphic bacterial human pathogens has given new insights into pathogen microevolution and phylogeography. Here, we report a genome-based micro-evolutionary...
- 14From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedHuman cytomegalovirus (HCMV), a herpesvirus, is a ubiquitously distributed pathogen that causes severe disease in immunosuppressed patients and infected newborns. Efforts are underway to prepare effective subunit...
- 15From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedVaccine and laboratory adapted strains of measles virus can use CD46 as a receptor to infect many human cell lines. However, wild type isolates of measles virus cannot use CD46, and they infect activated lymphocytes,...
- 16From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedUnderstanding the mechanism of infection control in elite controllers (EC) may shed light on the correlates of control of disease progression in HIV infection. However, limitations have prevented a clear understanding...
- 17From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedThe HIV/AIDS pandemic is a major global health threat and understanding the detailed molecular mechanisms of HIV replication is critical for the development of novel therapeutics. To replicate, HIV-1 must access the...
- 18From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedThe development of effective immunoprophylaxis against tuberculosis (TB) remains a global priority, but is hampered by a partially protective Bacillus Calmette-Guerin (BCG) vaccine and an incomplete understanding of the...
- 19From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedA significant number of environmental microorganisms can cause serious, even fatal, acute and chronic infections in humans. The severity and outcome of each type of infection depends on the expression of specific...
- 20From: PLoS Pathogens. (Vol. 7, Issue 8) Peer-ReviewedHighly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts. PB1-F2 is an alternative translation product of...