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- 1From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Eve Marder (corresponding author) [1]; Jean-Marc Goaillard [1] Humans, and other long-lived animals such as turtles and lobsters, have neurons that live and function well for decades. By contrast, ion...
- 2From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Avshalom Caspi (corresponding author) [1]; Terrie E. Moffitt (corresponding author) [1] Gene-environment interactions occur when the effect of exposure to an environmental pathogen on a person's health is...
- 3From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Helen C. Lai [1]; Lily Y. Jan (corresponding author) [2] Voltage-gated ion channels were among the first ion channels to be identified when voltage-clamp recordings were first undertaken over half a century...
- 4From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): John-Dylan Haynes (corresponding author) [1, 2, 3]; Geraint Rees [2, 3] Is it possible to tell what someone is currently thinking based only on measurements of their brain activity? At first sight, the...
- 5From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Arvind Govindarajan [1]; Raymond J. Kelleher [1, 2]; Susumu Tonegawa (corresponding author) [1] A key function of a neuron is to modify its response to synaptic input in an experience-dependent fashion. In...
- 6From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Ruth Williams Researchers from the University of British Columbia in Vancouver have gained new insight into the pathogenesis of Huntington's disease (HD). Their study shows that a particular modification to...
- 7From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Ari Joffe [1] Laureys stated that "brain death is death" [1] . The justification given for this statement is problematic. The stated concept of death is the "permanent cessation of the critical functions...
- 8From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Jane Qiu The human brain has the unique ability to represent the mental states of the self and others, and to make inferences about the relationship between them. Writing in Neuron , Jason Mitchell and...
- 9From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Daniel McGowan Neural crest cells are stem cells that appear along the border of the neural plate early in development, destined to differentiate into a wide variety of cell types throughout the body....
- 10From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Jane Qiu GABA ([gamma]-aminobutyric acid), the main inhibitory neurotransmitter in the vertebrate nervous system, has many modes of action. For one of its receptors GABAB -- a heterodimer consisting of...
- 11From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedEvidence has been accumulating that the primate cerebellum contributes not only to motor control, but also to higher 'cognitive' function. However, there is no consensus about how the cerebellum processes such...
- 12From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedIn many biological systems, there is a fine balance between stability and flexibility, and the brain's cells and circuitry are no exception. A major challenge faced by neurons and networks is to maintain long-term...
- 13From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Samantha Barton Endocannabinoids are unconventional neurotransmitters, travelling from a postsynaptic to a presynaptic neuron -- the opposite direction to typical chemical messengers. This signalling is...
- 14From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Katherine Whalley [1] The mechanism of action of most commonly used antidepressants is poorly defined and a better understanding of the effects of these drugs on the brain could lead to new therapeutic...
- 15From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Daniel McGowan Mutations in ion channels, usually characterized as producing either hyperexcitability or hypoexcitability, are associated with various neurological disorders. Now, Stephen Waxman and...
- 16From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Ruth Williams The development of post-mitotic neurons from neural precursors involves three steps: cell cycle exit, cell migration and cell differentiation. The cyclin-dependent kinase inhibitor p27kip1 is...
- 17From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedThe neurobiology of itch, which is formally known as pruritus, and its interaction with pain have been illustrated by the complexity of specific mediators, itch-related neuronal pathways and the central processing of...
- 18From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedSynaptic physiology Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis. Sutton, M. A. et al . Cell 125, 785-799 (2006) Long-term blockade of...
- 19From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Alison Rowan Ischaemic injury involves a pronounced reduction in oxygen and glucose around the affected area, which leads to rapid cell death that is associated with Ca 2+ , Na+ , K+ and Cl- dysregulation....
- 20From: Nature Reviews Neuroscience. (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Ruth Williams The stress of having to write this article in just 1 hour makes it easy to focus the mind. However, in normal daily life there is a constant barrage of distractions to contend with. For...