Showing Results for
- Academic Journals (21)
Search Results
- 21
Academic Journals
- 21
- Search Terms:
- 1From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Cecile Crosnier [1]; Despina Stamataki [1]; Julian Lewis [1] Each self-renewing tissue organizes the turnover of cells in its own way; but wherever the process depends on stem cells, the same fundamental...
- 2From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): David Kimelman [1] The vertebrate mesoderm produces a wide range of tissues including the muscles, heart, vasculature, blood, kidney, gonads, dermis and cartilage, and it also has a major role in the...
- 3From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Eric J. Richards [1] A unifying theme in biology is that the characteristics displayed by organisms are controlled -- ultimately -- by the nucleotide sequence of their genome. Another cornerstone of modern...
- 4From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Wallace Arthur [1] Evolutionary and developmental biology parted company from each other around 1900 and remained largely separate for about three-quarters of the twentieth century. They only began to...
- 5From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedBoth population-based and family-based designs are commonly used in genetic association studies to locate genes that underlie complex diseases. The simplest version of the family-based design -- the transmission...
- 6From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Magdalena Skipper How does the 1.5-fold increase in gene dosage on chromosome 21 lead to the many phenotypes of Down syndrome? New work shows that this pleiotropy can be traced back to two genes -- DSCR1...
- 7From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Jenny Bangham RNAi is widely used to knock down gene expression in plants. However, although it is a tremendously useful genetic tool, it is not perfect. The agents of RNAi, small interfering (siRNAs), are...
- 8From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedTechnology Cellulose synthase-like CsIF genes mediate the synthesis of cell wall (1,3;1,4)-[beta]-D -glucans . Burton, R. A. et al . Science 311, 1940-1942 (2006) The tough cell walls of many cereals consist...
- 9From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Magdalena Skipper Telomeres protect the ends of linear chromosomes and by doing so safeguard genome integrity. Although this fact is well known, much remains to be learnt about the structure and elongation...
- 10From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Sharon Ahmad [1] [illus. 1] Dosage compensation ensures that there are equal levels of X-linked gene products in males and females. In Drosophila melanogaster , this is achieved by doubling the transcript...
- 11From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): David B. Allison; Xiangqin Cui; Grier P. Page; Mahyar Sabripour Nature Reviews Genetics 7 55-65 (2006) In this article, the y -axis label for Figure 1d was incorrect. The correct y -axis label should be...
- 12From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Tanita Casci If we omit the details, then gene expression can be defined as resulting from the way in which a gene integrates the signals that operate on its regulatory control elements. But how do we...
- 13From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedRNA interference has re-energized the field of functional genomics by enabling genome-scale loss-of-function screens in cultured cells. Looking back on the lessons that have been learned from the first wave of...
- 14From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Louisa Flintoft An important breakthrough has been made in understanding the process that produces eggs or sperm in mammals. Contrary to previous theories that the two types of gamete are intrinsically...
- 15From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Katherine Whalley [1] RNAi has become a powerful research tool, but progress in developing therapeutic applications of this technology has only recently started to gather momentum. In a major advance for...
- 16From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedWhy do proteins evolve at different rates? Advances in systems biology and genomics have facilitated a move from studying individual proteins to characterizing global cellular factors. Systematic surveys indicate that...
- 17From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Tanita Casci Maps, smiley faces, triangles -- these are not the sort of objects one normally associates with DNA. But nanotechnology has found many uses for DNA that are beyond this molecule's natural...
- 18From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedLifespan Lipoprotein genotype and conserved pathway for exceptional longevity in humans . Atzmon, G. et al . PLoS Biol. 4, e113 (2006) This study took advantage of the limited genetic diversity among Ashkenazi...
- 19From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedThese days it's hard to imagine the world of functional genetics without the tools that RNAi has provided. The ability to knock down the function of a gene purely on the basis of knowing its sequence has proved...
- 20From: Nature Reviews Genetics. (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Tanita Casci Jade Williamson tells of spending her childhood wrapped head-to-toe in bandages, with daily trips to the hospital. Eczema sufferers like Jade therefore welcomed the news that the gene that...