Showing Results for
- Academic Journals (44)
Search Results
- 44
Academic Journals
- 44
- Search Terms:ISSN: 1553734XAndISSN: 15537358AndVolume Number: 7AndIssue Number: 3AndStart Page: e1001116AndDate: 2011 Revise Search
- 1From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedWe were pleased to see PLoS Conference Postcards return to the Pacific Symposium on Biocomputing (PSB), held January 4-11, 2011. This year we received a Postcard from A. Murat Eren, a PhD student at the University of...
- 2From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedAdaptation in spatially extended populations entails the propagation of evolutionary novelties across habitat ranges. Driven by natural selection, beneficial mutations sweep through the population in a ''wave of...
- 3From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedThe Ras superfamily comprises many guanine nucleotide-binding proteins (G proteins) that are essential to intracellular signal transduction. The guanine nucleotide-dependent intrinsic flexibility patterns of five G...
- 4From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedSensorimotor learning has been shown to depend on both prior expectations and sensory evidence in a way that is consistent with Bayesian integration. Thus, prior beliefs play a key role during the learning process,...
- 5From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedVoluntary motor commands produce two kinds of consequences. Initially, a sensory consequence is observed in terms of activity in our primary sensory organs (e.g., vision, proprioception). Subsequently, the brain...
- 6From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedTranscranial magnetic stimulation (TMS) is a stimulation method in which a magnetic coil generates a magnetic field in an area of interest in the brain. This magnetic field induces an electric field that modulates...
- 7From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedInferring the role of interactions in territorial animals relies upon accurate recordings of the behaviour of neighbouring individuals. Such accurate recordings are rarely available from field studies. As a result,...
- 8From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedSongs of many songbird species consist of variable sequences of a finite number of syllables. A common approach for characterizing the syntax of these complex syllable sequences is to use transition probabilities...
- 9From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedTumor necrosis factor [alpha] (TNF-[alpha]) is a key regulator of inflammation and rheumatoid arthritis (RA). TNF-[alpha] blocker therapies can be very effective for a substantial number of patients, but fail to work in...
- 10From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedThe depletion of cholesterol from membranes, mediated by b-cyclodextrin ([beta]-CD) is well known and documented, but the molecular details of this process are largely unknown. Using molecular dynamics simulations, we...
- 11From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedCell fate determination is usually described as the result of the stochastic dynamics of gene regulatory networks (GRNs) reaching one of multiple steady-states each of which corresponds to a specific decision. However,...
- 12From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedClassically, the functional consequences of natural selection over genomes have been analyzed as the compound effects of individual genes. The current paradigm for large-scale analysis of adaptation is based on the...
- 13From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedIn the past decade, over 50 genome-scale metabolic reconstructions have been built for a variety of single- and multicellular organisms. These reconstructions have enabled a host of computational methods to be leveraged...
- 14From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedIn natural ecosystems, hundreds of species typically share the same environment and are connected by a dense network of interactions such as predation or competition for resources. Much is known about how fixed...
- 15From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedInteraural time differences (ITDs) are the major cue for localizing low-frequency sounds. The activity of neuronal populations in the brainstem encodes ITDs with an exquisite temporal acuity of about 10 [micro]s. The...
- 16From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-Reviewed[CD8.sup.+] cytotoxic T lymphocytes (CTLs), natural killer (NK) cells, B cells and target cell limitation have all been suggested to play a role in the control of SIV and HIV-1 infection. However, previous research...
- 17From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedReactive oxygen species (ROS) produced in the mitochondrial respiratory chain (RC) are primary signals that modulate cellular adaptation to environment, and are also destructive factors that damage cells under the...
- 18From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedMicroRNAs are endogenous non-coding RNAs which negatively regulate the expression of protein-coding genes in plants and animals. They are known to play an important role in several biological processes and, together...
- 19From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedThe development of modern and affordable sequencing technologies has allowed the study of viral populations to an unprecedented depth. This is of particular interest for the study of within-host RNA viral populations,...
- 20From: PLoS Computational Biology. (Vol. 7, Issue 3) Peer-ReviewedThe mechanism of intra-protein communication and allosteric coupling is key to understanding the structure-property relationship of protein function. For subtilisin Carlsberg, the Ca2+-binding loop is distal to...