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- 1From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedIntroduction Randomised controlled trials, when appropriately designed, conducted, and reported, represent the gold standard in evaluating healthcare interventions. However, randomised trials can yield biased results...
- 2From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedBackground: There is a growing recognition that the provision of surgical services in low-income countries is inadequate to the need. While constrained health budgets and health worker shortages have been blamed for the...
- 3From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedThe Extent of the Problem Stroke, about 80% of which is ischaemic caused by occlusion of an intracerebral artery and 20% caused by intracerebral bleeding, is the second most common cause of death and disability...
- 4From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedBackground: Reduced saturated fat (SFA) consumption is recommended to reduce coronary heart disease (CHD), but there is an absence of strong supporting evidence from randomized controlled trials (RCTs) of clinical CHD...
- 5From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedBackground: There has been substantial research on psychosocial and health care determinants of health disparities in the United States (US) but less on the role of modifiable risk factors. We estimated the effects of...
- 6From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedAre Genetic Factors Important in Stroke Risk? Stroke is the third commonest cause of death and the major cause of adult neurological disability. It is a major health problem not only in the developed world, but is...
- 7From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedBackground: Many low- and middle-income countries are not on track to reach the public health targets set out in the Millennium Development Goals (MDGs). We evaluated whether differential progress towards health MDGs...
- 8From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedAdolescent binge drinking and related disorders are worldwide public health problems [1]. The European School Survey Project on Alcohol and Other Drugs [2] surveyed 16-year-old adolescents in 35 countries. Defined as...
- 9From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedIntroduction In its latest global assessment of road safety, the World Health Organization (WHO) reminded us that half of the 1.2 million fatalities occurring each year on the world's roads concern vulnerable road...
- 10From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedBackground: Men tend to have more upper body mass and fat than women, a physical characteristic that may predispose them to severe motor vehicle crash (MVC) injuries, particularly in certain body regions. This study...
- 11From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedBackground: Surgical conditions contribute significantly to the disease burden in sub-Saharan Africa. Yet there is an apparent neglect of surgical care as a public health intervention to counter this burden. There is...
- 12From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedBackground: Adoption of new and underutilized vaccines by national immunization programs is an essential step towards reducing child mortality. Policy decisions to adopt new vaccines in high mortality countries often...
- 13From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedAnimal experiments have contributed much to our understanding of mechanisms of disease, but their value in predicting the effectiveness of treatment strategies in clinical trials has remained controversial [1-3]. In...
- 14From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedNeonatal sepsis or septicaemia is a clinical syndrome characterized by systemic signs of circulatory compromise (e.g., poor peripheral perfusion, pallor, hypotonia, poor responsiveness) caused by invasion of the...
- 15From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedThis week in PLoS Medicine we publish a Policy Forum article by Lagarde and Constant on the prevention of injuries and deaths in vulnerable road users (VRUs) [1] and a research article by Shankuan Zhu and colleagues...
- 16From: PLoS Medicine. (Vol. 7, Issue 3) Peer-ReviewedChronic obstructive pulmonary disease (COPD) is a growing global epidemic that is particularly important in developing countries. Morbidity and mortality from COPD will rise as populations age and mortality from...