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- 1From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedSurgical complications are a major cause of avoidable medical mistakes, and might occur more frequently when surgery is performed at night. In a recent study, Lonze et al. found that patients who underwent liver...
- 2From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedStandard protocols for the diagnosis of neoplasms in the gastrointestinal tract are based on histopathologic analysis in combination with clinical information. With the completion of the Human Genome Project in 2003,...
- 3From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedFlorian Rieder and colleagues have demonstrated that prostaglandin E2 (PGE2) inhibits fibroblast migration in intestinal wound healing in patients who have IBD. Impaired wound healing is sometimes found in patients...
- 4From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedLam, P K. Y. et al. Clin. Gastroenterol. Hepatol. 8, 770-776 (2010) 82 patients with symptoms of laryngopharyngeal reflux were randomly allocated to receive 20 mg of the PPI rabeprazole or placebo twice daily....
- 5From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedFor at least the last four decades, pentoxifylline has been used as a palliative treatment for claudication in patients with peripheral vascular disease; however, this agent has yet to fulfill its potential as a...
- 6From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-Reviewed"Anonymous living donors are a reasonable source for donor livers for transplantation," says Trevor Reichman after conducting research into the outcomes of anonymous liver donors. In 2004, a middle-aged man...
- 7From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedChildren who have eosinophilic gastrointestinal disease (EGID) are at risk of feeding disorders that can persist even after eosinophilic inflammation is resolved, a recent study from the Us reports. Dan Atkins, a...
- 8From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedHelicobacter pylori plays an essential role in the development of various gastroduodenal diseases; however, only a small proportion of people infected with H. pylori develop these diseases. Some populations that have a...
- 9From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedWang, L.-D. et al. Nat. Genet. 42, 759-763 (2010) A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma Abnet, C. C. et al. Nat. Genet. 42, 764-767...
- 10From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedPrimary sclerosing cholangitis (PSC) is a chronic cholestatic liver disorder that most commonly affects middle-aged men. PSC is strongly associated with IBD, and in this setting the risk of colorectal cancer is markedly...
- 11From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedBackground. A 37-year-old female, who had a neuroendocrine pancreatic neoplasm, underwent duodeno-cephalo-pancreatectomy. In the 2 years following surgery, she had normal levels of serum chromogranin A (CgA), gastrin...
- 12From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedA preclinical study indicates that combinations of targeted therapies with erbB receptor tyrosine kinase inhibitors might have limited efficacy in patients with advanced cholangiocarcinoma. "Under particular conditions,...
- 13From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedEjskjaer, N. et al. Neurogastroenterol. Motil. 22, 1069-e281 (2010) TZP-101, a synthetic, selective ghrelin receptor agonist, is in clinical development for the treatment of patients with moderate to severe diabetic...
- 14From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedAnemia is the most prevalent extraintestinal complication of IBD. It can affect quality of life and ability to work, and can also increase the hospitalization rate in patients with IBD. Although the causes of anemia in...
- 15From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedAutophosphorylation of focal adhesion kinase (FAK) at tyrosine 397 (pTyr397) rather than FAK overexpression is associated with recurrence of gastric carcinomas, report Lai and colleagues from Taiwan. "Our study is the...
- 16From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-Reviewed"The inner mucus layer of the colon becomes permeable to bacteria after exposure to dextran sulfate," says Gunnar C. Hansson, corresponding author of a new study published in PLoS ONE. this finding could help explain...
- 17From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedEarly diagnosis of severe acute pancreatitis may be facilitated and patient outcomes improved by measuring serum levels of neutrophil gelatinase-associated lipocalin (NGAL). "We have identified a new, early biomarker...
- 18From: Nature Reviews Gastroenterology & Hepatology. (Vol. 7, Issue 11) Peer-ReviewedHyperplastic polyposis syndrome is a widely accepted, but poorly understood, risk factor for colorectal cancer. A recent report has laid the foundations for improving the management of patients with this enigmatic...