Showing Results for
- Academic Journals (60)
Search Results
- 60
Academic Journals
- 60
- Search Terms:ISSN: 15537366AndISSN: 15537374AndVolume Number: 7AndIssue Number: 10AndStart Page: e1002298AndDate: 2011 Revise Search
- 1From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedSeveral viruses encode factors that promote host mRNA degradation to silence gene expression. It is unclear, however, whether cellular mRNA turnover pathways are engaged to assist in this process. In Kaposi's...
- 2From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedNosocomial infections are increasingly being recognised as a major patient safety issue. The modern hospital environment and associated health care practices have provided a niche for the rapid evolution of microbial...
- 3From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedRecent sequencing projects have provided deep insight into fungal lifestyle-associated genomic adaptations. Here we report on the 25 Mb genome of the mutualistic root symbiont Piriformospora indica (Sebacinales,...
- 4From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedViruses have to encapsidate their own genomes during the assembly process. For most RNA viruses, there are sequences within the viral RNA and virion proteins needed for high efficiency of genome encapsidation. However,...
- 5From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedOxygen depletion of Mycobacterium tuberculosis engages the DosR regulon that coordinates an overall down-regulation of metabolism while up-regulating specific genes involved in respiration and central metabolism. We...
- 6From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedSystemic Lupus Erythematosus (SLE) pathology has long been associated with an increased Epstein-Barr Virus (EBV) seropositivity, viremia and cross-reactive serum antibodies specific for both virus and self. It has...
- 7From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedA subset of patients with stable asthma has prominent neutrophilic and reduced eosinophilic inflammation, which is associated with attenuated airways hyper-responsiveness (AHR). Haemophilus influenzae has been isolated...
- 8From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedInfection with the trematode parasite Schistosoma mansoni results in distinct heterogeneity of disease severity both in humans and in mice. In the experimental mouse model, severe disease is characterized by pronounced...
- 9From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedDuring the lytic phase of infection, the gamma herpesvirus Kaposi's Sarcoma-Associated Herpesvirus (KSHV) expresses a highly abundant, 1.1 kb nuclear noncoding RNA of unknown function. We observe that this...
- 10From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedIn order to design strategies for eradication of HIV-1 from infected individuals, detailed insight into the HIV-1 reservoirs that persist in patients on suppressive antiretroviral therapy (ART) is required. In this...
- 11From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedTelomerase reverse transcriptase (TERT) and telomerase RNA (TR) represent the enzymatically active components of telomerase. In the complex, TR provides the template for the addition of telomeric repeats to telomeres, a...
- 12From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedTo replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interferon effector genes (IEGs) that prevent viral replication. The interferon...
- 13From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedHepatitis C virus (HCV) core protein is directed to the surface of lipid droplets (LD), a step that is essential for infectious virus production. However, the process by which core is recruited from LD into nascent...
- 14From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedInfluenza A virus (IAV) enters host cells by endocytosis followed by acid-activated penetration from late endosomes (LEs). Using siRNA silencing, we found that histone deacetylase 8 (HDAC8), a cytoplasmic enzyme,...
- 15From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedDuring hematogenously disseminated disease, Candida albicans infects most organs, including the brain. We discovered that a C. albicans vps51 [DELTA]/[DELTA] mutant had significantly increased tropism for the brain in...
- 16From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedGammaherpesviruses such as KSHV and EBV establish lifelong persistent infections through latency in lymphocytes. These viruses have evolved several strategies to counteract the various components of the innate and...
- 17From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedChikungunya virus (CHIKV) is a re-emerging alphavirus that has caused significant disease in the Indian Ocean region since 2005. During this outbreak, in addition to fever, rash and arthritis, severe cases of CHIKV...
- 18From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedEpstein-Barr virus (EBV) is a human lymphocryptovirus that is associated with several malignancies. Elevated EBV DNA in the blood is observed in transplant recipients prior to, and at the time of post- transplant...
- 19From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedApicomplexan parasites rely on a novel form of actin-based motility called gliding, which depends on parasite actin polymerization, to migrate through their hosts and invade cells. However, parasite actins are divergent...
- 20From: PLoS Pathogens. (Vol. 7, Issue 10) Peer-ReviewedCytomegalovirus (CMV) is a [beta]-herpesvirus that establishes a lifelong latent or persistent infection. A hallmark of chronic CMV infection is the lifelong persistence of large numbers of virus-specific CD8+...