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- Search Terms:ISSN: 15537366AndISSN: 15537374AndVolume Number: 7AndIssue Number: 1AndStart Page: e1001255AndDate: 2011 Revise Search
- 1From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedNatural killer (NK) cells and [CD8.sup.+] T cells play vital roles in containing and eliminating systemic cytomegalovirus (CMV). However, CMV has a tropism for the salivary gland acinar epithelial cells and persists in...
- 2From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedNon-typeable Haemophilus influenzae (NTHi), a common commensal of the human pharynx, is also an opportunistic pathogen if it becomes established in the lower respiratory tract (LRT). In comparison to colonizing isolates...
- 3From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedPrions, the agents causing transmissible spongiform encephalopathies, colonize the brain of hosts after oral, parenteral, intralingual, or even transdermal uptake. However, prions are not generally considered to be...
- 4From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedSeveral candidate gene studies have provided evidence for a role of host genetics in susceptibility to tuberculosis (TB). However, the results of these studies have been very inconsistent, even within a study...
- 5From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedThe ultimate stage of the transmission of Dengue Virus (DENV) to man is strongly dependent on crosstalk between the virus and the immune system of its vector Aedes aegypti (Ae. aegypti). Infection of the mosquito's...
- 6From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedViruses in the Flavivirus genus of the Flaviviridae family are arthropod-transmitted and contribute to staggering numbers of human infections and significant deaths annually across the globe. To identify cellular...
- 7From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedA large group of viruses rely on low pH to activate their fusion proteins that merge the viral envelope with an endosomal membrane, releasing the viral nucleocapsid. A critical barrier to understanding these events has...
- 8From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedParasitic worms alter their host's immune system to diminish the inflammatory responses directed against them, using very efficient immunomodulating molecules. We have previously shown that the helminth immunomodulator...
- 9From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedThe bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1. Here, we show that lysosomal membrane permeabilization (LMP)...
- 10From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedBacterial extracellular polysaccharides are a key constituent of the extracellular matrix material of biofilms. Pseudomonas aeruginosa is a model organism for biofilm studies and produces three extracellular...
- 11From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedRecent cross-sectional analyses of HIV-1+ plasmas have indicated that broadly cross-reactive neutralizing antibody responses are developed by 10%-30% of HIV-1+ subjects. The timing of the initial development of such...
- 12From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedAt the height of World War I, the human population was assaulted by a powerful, but very small, foreign agent that rapidly appeared seemingly from nowhere. Ultimately identified as the "Spanish flu", this agent wreaked...
- 13From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedInterferon-inducible transmembrane proteins 1, 2, and 3 (IFITM1, 2, and 3) are recently identified viral restriction factors that inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein....
- 14From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedThe herpesvirus proteins HSV-1 ICP27 and HVS ORF57 promote viral mRNA export by utilizing the cellular mRNA export machinery. This function is triggered by binding to proteins of the transcription-export (TREX) complex,...
- 15From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedThe transcription factor Interferon Regulatory Factor 5 (IRF-5) has been shown to be involved in the induction of proinflammatory cytokines in response to viral infections and TLR activation and to play an essential...
- 16From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedThe global security community continues to view a potential bioterrorist event with concern. Kofi Annan, former Secretary General of the United Nations, stated "the most important under-addressed threat relating to...
- 17From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedMeasles virus (MV) is highly infectious, and has long been thought to enter the host by infecting epithelial cells of the respiratory tract. However, epithelial cells do not express signaling lymphocyte activation...
- 18From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedYersinia pseudotuberculosis forms biofilms on Caenorhabditis elegans which block nematode feeding. This genetically amenable host-pathogen model has important implications for biofilm development on living, motile...
- 19From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedSurface recognition and penetration are among the most critical plant infection processes in foliar pathogens. In Magnaporthe oryzae, the Pmk1 MAP kinase regulates appressorium formation and penetration. Its orthologs...
- 20From: PLoS Pathogens. (Vol. 7, Issue 1) Peer-ReviewedC-type lectins dectin-1 and dectin-2 on dendritic cells elicit protective immunity against fungal infections through induction of [T.sub.H]1 and [T.sub.H]-17 cellular responses. Fungal recognition by dectin-1 on human...