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- Search Terms:ISSN: 19352727AndISSN: 19352735AndVolume Number: 6AndIssue Number: 8AndStart Page: e1794AndDate: 2012 Revise Search
- 1From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: Rift Valley fever (RVF) is a zoonotic arbovirosis for which the primary hosts are domestic livestock (cattle, sheep and goats). RVF was first described in South Africa in 1950-1951. Mechanisms for short and...
- 2From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedThe emergence of highly chloroquine (CQ) resistant P. vivax in Southeast Asia has created an urgent need for an improved understanding of the mechanisms of drug resistance in these parasites, the development of robust...
- 3From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: In recent years, new strategies aimed at reducing the capacity of mosquito vectors to transmit dengue fever have emerged. As with earlier control methods, they will have to be employed in a diverse range of...
- 4From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedWe analyzed the transcriptional signatures of mouse bone marrow-derived macrophages at different times after infection with promastigotes of the protozoan parasite Leishmania major. Ingenuity Pathway Analysis revealed...
- 5From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: Rift Valley fever (RVF) is a vector-borne viral zoonosis of increasing global importance. RVF virus (RVFV) is transmitted either through exposure to infected animals or through bites from different species...
- 6From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedDiseases such as trypanosomiasis, leishmaniasis, and lymphatic filariasis impose substantial health burdens in developing countries [1,2]. These diseases are widely neglected because there is little financial incentive...
- 7From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: Sleeping sickness, also called human African trypanosomiasis, is transmitted by the tsetse, a blood-sucking fly confined to sub-Saharan Africa. The form of the disease in West and Central Africa is carried...
- 8From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: Trypanosoma cruzi is the etiological agent of Chagas disease, a debilitating illness that affects millions of people in the Americas. A major finding of the T. cruzi genome project was the discovery of a...
- 9From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedIntroduction Parasitic protozoa are important agents of human and veterinary diseases, which are widely distributed throughout the world. The parasite Trypanosoma cruzi, which is the causal agent of the human disease...
- 10From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedObjective: Human toxocariasis is a zoonotic infection caused by the larval stages of Toxocara canis (T. canis) and less frequently Toxocara cati (T. cati). A relationship between toxocariasis and epilepsy has been...
- 11From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: A. aegypti production and human density may vary considerably in dengue endemic areas. Understanding how interactions between these factors influence the risk of transmission could improve the effectiveness...
- 12From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: Trachomatous trichiasis (TT) surgery is provided free or subsidised in most trachoma endemic settings. However, only 18-66% of TT patients attend for surgery. This study analyses barriers to attendance among...
- 13From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: The Bolivian northern Altiplano is characterized by a high prevalence of Fasciola hepatica infection. In order to assess the feasibility, safety and efficacy of large-scale administration of triclabendazole...
- 14From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: The trehalose metabolic enzymes have been considered as potential targets for drug or vaccine in several organisms such as Mycobacterium, plant nematodes, insects and fungi due to crucial role of sugar...
- 15From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: The protozoan parasite Giardia intestinalis and the pathogenic bacterium Helicobacter pylori are well known for their high prevalences in human hosts worldwide. The prevalence of both organisms is known to...
- 16From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedPresentation of Case A 27-year-old male farmer presented himself to an integrated health centre in the Bankim health district of the Adamaoua region of Cameroon with two ulcerative lesions with undermined edges on...
- 17From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: Zika virus (ZIKV) is a little known flavivirus that caused a major outbreak in 2007, in the South-western Pacific Island of Yap. It causes dengue-like syndromes but with milder symptoms. In Africa, where it...
- 18From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: Despite the availability of effective interventions and public recognition of the severity of the problem, rabies continues to suffer neglect by programme planners in India and other low and middle income...
- 19From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: Systemic leishmaniasis has been known to present with prolonged fever, hepatosplenomegaly and wasting. Beside this classical form, a sub-clinical form has been identified. It is described with either one or...
- 20From: PLoS Neglected Tropical Diseases. (Vol. 6, Issue 8) Peer-ReviewedBackground: Dengue is a growing problem both in its geographical spread and in its intensity, and yet current global distribution remains highly uncertain. Challenges in diagnosis and diagnostic methods as well as...