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Academic Journals
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- Search Terms:ISSN: 15537390AndISSN: 15537404AndVolume Number: 6AndIssue Number: 5AndStart Page: e1000934AndDate: 2010 Revise Search
- 1From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedThe radically distinct morphologies of arthropod and tetrapod legs argue that these appendages do not share a common evolutionary origin. Yet, despite dramatic differences in morphology, it has been known for some time...
- 2From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedThe plant life cycle alternates between two distinct multi-cellular generations, the reduced gametophytes and the dominant sporophyte. Little is known about how generation-specific cell fate, differentiation, and...
- 3From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedDNA replication programs have been studied extensively in yeast and animal systems, where they have been shown to correlate with gene expression and certain epigenetic modifications. Despite the conservation of core DNA...
- 4From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedEpidemiological studies have shown that one of the strongest risk factors for prostate cancer is a family history of the disease, suggesting that inherited factors play a major role in prostate cancer susceptibility....
- 5From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedThe optic nerve head is involved in many ophthalmic disorders, including common diseases such as myopia and open-angle glaucoma. Two of the most important parameters are the size of the optic disc area and the vertical...
- 6From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedCodon usage bias in prokaryotic genomes is largely a consequence of background substitution patterns in DNA, but highly expressed genes may show a preference towards codons that enable more efficient and/or accurate...
- 7From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedAlthough more than 2,400 genes have been shown to contain variants that cause Mendelian disease, there are still several thousand such diseases yet to be molecularly defined. The ability of new whole-genome sequencing...
- 8From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedTo get beyond the "low-hanging fruits" so far identified by genome-wide association (GWA) studies, new methods must be developed in order to discover the numerous remaining genes that estimates of heritability indicate...
- 9From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedMeiosis halves the chromosome number because its two divisions follow a single round of DNA replication. This process involves two cell transitions, the transition from prophase to the first meiotic division (meiosis I)...
- 10From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedGenetic factors play an important role in the etiology of breast cancer. We carried out a multi-stage genome-wide association (GWA) study in over 28,000 cases and controls recruited from 12 studies conducted in Asian...
- 11From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedChromosome termini for specialized type of heterochromatin that is important for chromosome stability. The recent discovery of telomeric RNA transcripts in yeast and ebrates raised the question of whether RNA--based...
- 12From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedThe aphid Myzus persicae is a globally significant crop pest that has evolved high levels of resistance to almost all classes of insecticide. To date, the neonicotinoids, an economically important class of insecticides...
- 13From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedProtein palmitoylation has emerged as an important mechanism for regulating protein trafficking, stability, and proteinprotein interactions;however, its relevance to disease processes is not clear. Using a genome-wide,...
- 14From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedAlthough the decision to proceed through cell division depends largely on the metabolic status or the size of the cell, the timing of cell division is often set by internal clocks such as the circadian clock. Light is a...
- 15From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedAlthough little is known about the role of the cystic fibrosis transmembrane regulator (CFTR) gene in reproductive physiology, numerous variants in this gene have been implicated in etiology of male infertility due to...
- 16From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedCell-fate specification is typically thought to precede and determine cell-cycle regulation during differentiation. Here we show that endoreplication, also known as endoreduplication, a specialized cell-cycle variant...
- 17From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedHuman chromosome 14q32.2 harbors the germline-derived primary DLK1-MEG3 intergenic differentially methylated region (IG-DMR) and the postfertilization-derived secondary MEG3-DMR, together with multiple imprinted genes....
- 18From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedThe function of the tumor suppressor RE1 silencing transcription factor (REST) is lost in colon and small cell lung cancers and is known to induce anchorage-independent growth in human mammary epithelial cells. However,...
- 19From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedThe increased transcription of the Cyp6g1 gene of Drosophila melanogaster, and consequent resistance to insecticides such as DDT, is a widely cited example of adaptation mediated by cis-regulatory change. A fragment of...
- 20From: PLoS Genetics. (Vol. 6, Issue 5) Peer-ReviewedTesting for genetic effects on mean values of a quantitative trait has been a very successful strategy. However, most studies to date have not explored genetic effects on the variance of quantitative traits as a...