Showing Results for
- Academic Journals (31)
Search Results
- 31
Academic Journals
- 31
- Search Terms:ISSN: 15537366AndISSN: 15537374AndVolume Number: 6AndIssue Number: 12AndStart Page: e1001249AndDate: 2010 Revise Search
- 1From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedWhat Are Candida Species and Why Are They Important? Historically, Candida species represented a catch-all taxonomic grouping for yeasts that exhibited hyphal or pseudohyphal branching and did not form sexual spores....
- 2From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedMyeloid dendritic cells (mDC) are lost from blood in individuals with human immunodeficiency virus (HIV) infection but the mechanism for this loss and its relationship to disease progression are not known. We studied...
- 3From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-Reviewed
Evidence that intracellular stages of Leishmania major utilize amino sugars as a major carbon source
Intracellular parasites, such as Leishmania spp, must acquire suitable carbon sources from the host cell in order to replicate. Here we present evidence that intracellular amastigote stages of Leishmania exploit amino... - 4From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedClimate warming is predicted to increase the frequency of invasions by pathogens and to cause the large-scale redistribution of native host species, with dramatic consequences on the health of domesticated and wild...
- 5From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedThe neotropical Drosophila paulistorum superspecies, consisting of at least six geographically overlapping but reproductively isolated semispecies, has been the object of extensive research since at least 1955, when it...
- 6From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedKSHV is etiologically associated with Kaposi's sarcoma (KS), an angioproliferative endothelial cell malignancy. Macropinocytosis is the predominant mode of in vitro entry of KSHV into its natural target cells, human...
- 7From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedWe previously showed that broadly neutralizing anti-HIV-1 antibody 2G12 (human IgG1) naturally forms dimers that are more potent than monomeric 2G12 in in vitro neutralization of various strains of HIV-1. In this study,...
- 8From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedEpstein-Barr virus (EBV) is associated with human malignancies, especially those affecting the B cell compartment such as Burkitt lymphoma. The virally encoded homolog of the mammalian pro-survival protein Bcl-2, BHRF1...
- 9From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedMycoplasma pneumoniae is one of the most common causes of respiratory infections in children and adults worldwide [1,2]. This bacterial pathogen is estimated to be responsible for at least one case of pneumonia per...
- 10From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedParasitic protozoa such as the apicomplexan Toxoplasma gondii progress through their life cycle in response to stimuli in the environment or host organism. Very little is known about how proliferating tachyzoites...
- 11From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedStudies in malaria patients indicate that higher frequencies of peripheral blood CD[4.sup.+] Foxp[3.sup.+] CD[25.sup.+] regulatory T (Treg) cells correlate with increased blood parasitemia. This observation implies that...
- 12From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedEpigenetic regulatory mechanisms and their enzymes are promising targets for malaria therapeutic intervention; however, the epigenetic component of gene expression in P. falciparum is poorly understood. Dynamic or...
- 13From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedOur ability to control diseases caused by parasitic nematodes is constrained by a limited portfolio of effective drugs and a paucity of robust tools to investigate parasitic nematode biology. RNA interference (RNAi) is...
- 14From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedIntroduced in the 1950s, ethidium bromide (EB) is still used as an anti-trypanosomal drug for African cattle although its mechanism of killing has been unclear and controversial. EB has long been known to cause loss of...
- 15From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedThe V3 loop of the HIV-1 Env protein is the primary determinant of viral coreceptor usage, whereas the V1V2 loop region is thought to influence coreceptor binding and participate in shielding of neutralization-sensitive...
- 16From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedThe importance of honey bees to the world economy far surpasses their contribution in terms of honey production;they are responsible for up to 30% of the world's food production through pollination of crops. Since fall...
- 17From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedMalaria, caused by the apicomplexan parasite Plasmodium, still represents a major threat to human health and welfare and leads to about one million human deaths annually. Plasmodium is a rapidly multiplying unicellular...
- 18From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedNK cells are enriched in the liver, constituting around a third of intrahepatic lymphocytes. We have previously demonstrated that they upregulate the death ligand TRAIL in patients with chronic hepatitis B virus...
- 19From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedProductive replication of DNA viruses elicits host cell DNA damage responses, which cause both beneficial and detrimental effects on viral replication. In response to the viral productive replication, host cells attempt...
- 20From: PLoS Pathogens. (Vol. 6, Issue 12) Peer-ReviewedDisruption of p53/Puma-mediated apoptosis protects against lethality due to DNA damage. Here we demonstrate the unexpected requirement of the pro-apoptotic p53-target gene Puma to mount a successful innate immune...