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- Search Terms:ISSN: 15537366AndISSN: 15537374AndVolume Number: 5AndIssue Number: 5AndStart Page: e1000437AndDate: 2009 Revise Search
- 1From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedThe mitochondrial [F.sub.0][F.sub.1] ATP synthase is an essential multi-subunit protein complex in the vast majority of eukaryotes but little is known about its composition and role in Trypanosoma brucei, an early...
- 2From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedMalaria-transmitting mosquitoes are continuously exposed to microbes, including their midgut microbiota. This naturally acquired microbial flora can modulate the mosquito's vectorial capacity by inhibiting the...
- 3From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedListeria monocytogenes is a human intracellular pathogen able to colonize host tissues after ingestion of contaminated food, causing severe invasive infections. In order to gain a better understanding of the nature of...
- 4From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedThe hemolytic phospholipase C (PIcHR) expressed by Pseudomonas aeruginosa is the original member of a Phosphoesterase Superfamily, which includes phosphorylcholine-specific phospholipases C (PC-PLC) produced by frank...
- 5From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedHelicobacter pylori (Hp) intimately interacts with the gastric epithelial surface and translocates the virulence factor CagA into host cells in a contact-dependent manner. To study how Hp benefits from interacting with...
- 6From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedAnthrax lethal toxin (LT) induces vascular insufficiency in experimental animals through unknown mechanisms. In this study, we show that neuronal nitric oxide synthase (nNOS) deficiency in mice causes strikingly...
- 7From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedPlasmodium falciparum is the major human malaria agent responsible for 200 to 300 million infections and one to three million deaths annually, mainly among African infants. The origin and evolution of this pathogen...
- 8From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedDeveloping an immunogen that elicits broadly neutralizing antibodies (bNAbs) is an elusive but important goal of HIV vaccine research, especially after the recent failure of the leading T cell based HIV vaccine in human...
- 9From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedTuberculous latency and reactivation play a significant role in the pathogenesis of tuberculosis, yet the mechanisms that regulate these processes remain unclear. The Mycobacterium tuberculosis universal stress protein...
- 10From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedStaphylococcus epidermidis remains the predominant pathogen in prosthetic-device infections. Ventricular assist devices, a recently developed form of therapy for end-stage congestive heart failure, have had considerable...
- 11From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedMicrobial pathogenesis studies traditionally encompass dissection of virulence properties such as the bacterium's ability to elaborate toxins, adhere to and invade host cells, cause tissue damage, or otherwise disrupt...
- 12From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedPathogens, which alternate between environmental reservoirs and a mammalian host, frequently use thermal sensing devices to adjust virulence gene expression. Here, we identify the Yersinia virulence regulator RovA as a...
- 13From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedThe influenza A viruses genome comprises eight single-stranded RNA segments of negative polarity. Each one is included in a ribonucleoprotein particle (vRNP) containing the polymerase complex and a number of...
- 14From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedIntracellular pathogens must withstand nitric oxide (NO*) generated by host phagocytes. Salmonella enterica serovar Typhimurium interferes with intracellular trafficking of inducible nitric oxide synthase (iNOS) and...
- 15From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedUnderstanding the pathogenesis of infection by neurotropic viruses represents a major challenge and may improve our knowledge of many human neurological diseases for which viruses are thought to play a role. Borna...
- 16From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedTo support their replication, viruses take advantage of numerous cellular factors and procesins. Recent large-scale screens have identified hundreds of such factors, yet little is known about how viruses exploit any of...
- 17From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedThe advantages of the mouse as a model organism in biomedical research are many. The molecular and genetic toolbox developed for the mouse over the last 100 years enables researchers to manipulate and study gene...
- 18From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedLike several other intracellular pathogens, Mycobacterium marinum (Mm) escapes from phagosomes into the host cytosol where it can polymerize actin, leading to motility that promotes spread to neighboring cells. However,...
- 19From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedCowpea mosaic virus (CPMV) is a plant comovirus in the picornavirus superfamily, and is used for a wide variety of biomedical and material science applications. Although its replication is restricted to plants, CPMV...
- 20From: PLoS Pathogens. (Vol. 5, Issue 5) Peer-ReviewedSince the outbreak of severe acute respiratory syndrome (SARS) in 2003, the three-dimensional structures of several of the replicase/transcriptase components of SARS coronavirus (SARS-CoV), the non-structural proteins...