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- Search Terms:ISSN: 15491277AndISSN: 15491676AndVolume Number: 5AndIssue Number: 5AndStart Page: e95AndDate: 2008 Revise Search
- 1From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedIn December 1995, results from the National Institute for Neurological Disorders (NINDS) Recombinant Tissue Plasminogen Activator (rt-PA) Stroke Trial were published [1]. The implications of this trial have been...
- 2From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedBackground Individuals' expectations on returning to work after an injury have been shown to predict the duration of time that a person with work-related low back pain will remain on benefits; individuals with lower...
- 3From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedThe relationship between alcohol sales, alcohol consumption patterns, and levels of violence is well established. In a meta-analysis of data from seven countries, Jason Bond and colleagues estimated that the fraction of...
- 4From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedBackground Previously, we demonstrated that hypofibrinolysis, a decreased capacity to dissolve a blood clot as measured with an overall clot lysis assay, increases the risk of venous thrombosis. Here, we investigated...
- 5From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedBackground Virus-specific [CD8.sup.+] T lymphocytes play a key role in the initial reduction of peak viremia during acute viral infections, but display signs of increasing dysfunction and exhaustion under conditions...
- 6From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedThe human immune system is extraordinarily active against infection with HIV-1, yet never eliminates the virus and rarely controls viral replication for prolonged periods without the assistance of anti-retroviral...
- 7From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedIn the last decade or so, we have become familiar with the discovery of new classes of nuclear encoded regulators (see Glossary) as fundamental controllers of gene expression. Each new discovery has again highlighted...
- 8From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedWherever medical resources are scarce and access to medical care is limited, as in most of the developing world, medical researchers face difficult issues about providing medical care beyond the purview of their...
- 9From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedBackground Testing pregnant women for HIV at the time of labor and delivery is the last opportunity for prevention of mother-to-child HIV transmission (PMTCT) measures, particularly in settings where women do not...
- 10From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedStandard care for HIV antiretroviral treatment in resource-rich regions of the world includes HIV RNA monitoring every three to four months for viral rebound (i.e., an increase in HIV RNA to detectable levels following...
- 11From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedBackground Alcohol is a contributing cause of unintentional injuries, such as motor vehicle crashes. Prior research on the association between alcohol use and violent injury was limited to survey-based data, and the...
- 12From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedBackground Vascular endothelial growth factor-A (VEGF) is one of the key regulators of tumor development, hence it is considered to be an important therapeutic target for cancer treatment. However, clinical trials...
- 13From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedCorrection for: Ezzati M, Friedman AB, Kulkarni SC, Murray CJL (2008) The reversal of fortunes: Trends in county mortality and cross- county mortality disparities in the United States. PLoS Med 5(4): e66....
- 14From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedDisease mongering is the selling of sickness that widens the boundaries of illness in order to grow markets for those who sell and deliver treatments. It is a process that turns healthy people into patients, causes...
- 15From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedBackground Although environmental lead exposure is associated with significant deficits in cognition, executive functions, social behaviors, and motor abilities, the neuroanatomical basis for these impairments...
- 16From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedOn April 26, 2007, ABC World News, the American Broadcasting Corporation's flagship television news program, aired a "good news" story about a new test for prostate cancer [1]. Against a background of a dramatic graphic...
- 17From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedBackground The identification and characterization of tumor suppressor genes has enhanced our understanding of the biology of cancer and enabled the development of new diagnostic and therapeutic modalities. Whereas...
- 18From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedBackground Childhood lead exposure is a purported risk factor for antisocial behavior, but prior studies either relied on indirect measures of exposure or did not follow participants into adulthood to examine the...
- 19From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedNews stories about new treatments, tests, products, and procedures appear daily. Such reporting should ideally be accurate, balanced, and complete so that health care consumers are properly informed and ready to...
- 20From: PLoS Medicine. (Vol. 5, Issue 5) Peer-ReviewedAmong environmental chemicals, lead's reputation as a "bad actor" is confirmed in study after study. Over the past 30 years, we have learned that its toxicities are expressed in many forms, and, unfortunately, at levels...