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- Search Terms:ISSN: 1553734XAndISSN: 15537358AndVolume Number: 5AndIssue Number: 3AndStart Page: e1000334AndDate: 2009 Revise Search
- 1From: PLoS Computational Biology. (Vol. 5, Issue 3) Peer-ReviewedThe profusion of high-throughput instruments and the explosion of new results in the scientific literature, particularly in molecular biomedicine, is both a blessing and a curse to the bench researcher. Even...
- 2From: PLoS Computational Biology. (Vol. 5, Issue 3) Peer-ReviewedMany important protein-protein interactions are mediated by the binding of a short peptide stretch in one protein to a large globular segment in another. Recent efforts have provided hundreds of examples of new peptides...
- 3From: PLoS Computational Biology. (Vol. 5, Issue 3) Peer-ReviewedAmyloids and prion proteins are clinically and biologically important [beta]-structures, whose supersecondary structures are difficult to determine by standard experimental or computational means. In addition,...
- 4From: PLoS Computational Biology. (Vol. 5, Issue 3) Peer-ReviewedNumerous psychophysical experiments found that humans preferably rely on a narrow band of spatial frequencies for recognition of face identity. A recently conducted theoretical study by the author suggests that this...
- 5From: PLoS Computational Biology. (Vol. 5, Issue 3) Peer-ReviewedAdipose tissue grows by two mechanisms: hyperplasia (cell number increase) and hypertrophy (cell size increase). Genetics and diet affect the relative contributions of these two mechanisms to the growth of adipose...
- 6From: PLoS Computational Biology. (Vol. 5, Issue 3) Peer-ReviewedUnderstanding the relationship between genetic variation and gene expression is a central question in genetics. With the availability of data from high-throughput technologies such as ChIP-Chip, expression, and...
- 7From: PLoS Computational Biology. (Vol. 5, Issue 3) Peer-ReviewedStructural classifications of proteins assume the existence of the fold, which is an intrinsic equivalence class of protein domains. Here, we test in which conditions such an equivalence class is compatible with...
- 8From: PLoS Computational Biology. (Vol. 5, Issue 3) Peer-ReviewedA new method is presented for extraction of population firing-rate models for both thalamocortical and intracortical signal transfer based on stimulus-evoked data from simultaneous thalamic single-electrode and cortical...
- 9From: PLoS Computational Biology. (Vol. 5, Issue 3) Peer-ReviewedSelf-organized criticality is an attractive model for human brain dynamics, but there has been little direct evidence for its existence in large-scale systems measured by neuroimaging. In general, critical systems are...
- 10From: PLoS Computational Biology. (Vol. 5, Issue 3) Peer-ReviewedIn this era of complete genomes, our knowledge of neuroanatomical circuitry remains surprisingly sparse. Such knowledge is critical, however, for both basic and clinical research into brain function. Here we advocate...