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- Search Terms:ISSN: 15491277AndISSN: 15491676AndVolume Number: 5AndIssue Number: 3AndStart Page: e52AndDate: 2008 Revise Search
- 1From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedThe mosquito Aedes aegypti is the primary vector of three important viral diseases--dengue, yellow fever, and chikungunya--and is capable of transmitting a number of others. Ae. aegypti, which bites during daylight, is...
- 2From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedBackground Rituximab is used in the treatment of [CD20.sup.+] B cell lymphomas and other B cell lymphoproliferative disorders. Its clinical efficacy might be further improved by combinations with other drugs such as...
- 3From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedIn this Essay, we offer reflections based on our previously published ethnographic study of physician and patient responses to lifeextending cardiac procedures that are increasingly performed on ever older individuals...
- 4From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedBackground Mathematical modelling of infectious diseases transmitted by the respiratory or close-contact route (e.g., pandernic influenza) is increasingly being used to determine the impact of possible interventions....
- 5From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedBackground CD20 is a cell surface marker expressed on mature B cells and most malignant B cells. It does not modulate rapidly, is not shed, and is highly expressed, leading to its use as a target for immunotherapy....
- 6From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedBackground The developmental overnutrition hypothesis suggests that greater maternal obesity during pregnancy results in increased offspring adiposity in later life. If true, this would result in the obesity epidemic...
- 7From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedKay-Tee Khaw, Nicholas Wareham, Sheila Bingham, Ailsa Welch, Robert Luben, Nicholas Day Correction for: Khaw KT, Wareham N, Bingham S, Welch A, Luben R, et al. (2008) Combined impact of health behaviours and...
- 8From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedSurveillance, according to the World Health Organization (WHO), "is the cornerstone of public health security" [1]. In many developing countries, human, laboratory, and infrastructure limitations impede effective...
- 9From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedBackground An outbreak of chikungunya virus affected over one-third of the population of La R6union Island between March 2005 and December 2006. In June 2005, we identified the first case of mother-to-child...
- 10From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedIn Europe, it is a legal requirement to conduct clinical trials in accordance with the International Conference on Harmonisation's guidelines on good clinical practice (see http://www.ich.org/). A recent editorial...
- 11From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedBackground MUC2 mucin produced by intestinal goblet cells is the major component of the intestinal mucus barrier. The inflammatory bowel disease ulcerative colitis is characterized by depleted goblet cells and a...
- 12From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedOne need look no further than Facebook to appreciate the significance and power of social networking. (Even PLoS has its own thriving Facebook community, which you can join at...
- 13From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedBackground The structure of sexual contact networks plays a key role in the epidemiology of sexually transmitted infections, and their reconstruction from interview data has provided valuable insights into the spread...
- 14From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedChildhood obesity has become a serious public health problem worldwide. The United States Centers for Disease Control and Prevention estimates that one in three children and adolescents are currently overweight/obese...
- 15From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedBackground The acquired component of complex traits is difficult to dissect in humans. Obesity represents such a trait, in which the metabolic and molecular consequences emerge from complex interactions of genes and...
- 16From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedTwo views about medical science seem to have split ever more apart over the past decades. One view is that of medical researchers who rejoice in discoveries and explanations of causes of disease. Discoveries happen when...
- 17From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedBackground to the debate: The advent of highly active antiretroviral therapy (HAART) dramatically improved the prognosis for both adults and children infected with HIV who had access to treatment. However, the optimal...
- 18From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedThe critical role of breast-feeding in improving infant and under-five-year survival in resource-limited settings has been well documented since the mid-1970s. A pooled analysis by the World Health Organization (WHO) of...
- 19From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedBackground The heritable haemoglobinopathy [[alpha].sup.+]-thalassaemia is caused by the reduced synthesis of [alpha]-globin chains that form part of normal adult haemoglobin (Hb). Individuals homozygous for...
- 20From: PLoS Medicine. (Vol. 5, Issue 3) Peer-ReviewedDespite the range of resources directed at understanding the HIV pandemic over the past 25 years, surprisingly little is known about how HIV infection spreads through populations. Unlike some other infectious diseases,...