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- Search Terms:ISSN: 15537366AndISSN: 15537374AndVolume Number: 5AndIssue Number: 2AndStart Page: e1000292AndDate: 2009 Revise Search
- 1From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedInfectious diseases of the nervous system in the developing world have been relatively neglected. This is paradoxical because neurotropic pathogens are common and contribute significantly to human suffering and disease...
- 2From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedLyme disease Borrelia can infect humans and animals for months to years, despite the presence of an active host immune response. The vls antigenic variation system, which expresses the surface-exposed lipoprotein VlsE,...
- 3From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedA number of studies have shown that both innate and adaptive immune defense mechanisms greatly influence the course of human dengue virus (DENV) infections, but little is known about the innate immune response of the...
- 4From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedDicer ribonucleases of plants and invertebrate animals including Caenorhabditis elegans recognize and process a viral RNA trigger into virus-derived small interfering RNAs (siRNAs) to guide specific viral immunity by...
- 5From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedPlant microRNAs (miRNA) guide cleavage of target mRNAs by DICER-like proteins, thereby reducing mRNA abundance. Native precursor miRNAs can be redesigned to target RNAs of interest, and one application of such artificial...
- 6From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedType 1 fimbriae are a crucial factor for the virulence of uropathogenic Escherichia coli during the first steps of infection by mediating adhesion to epithelial cells. They are also required for the consequent...
- 7From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedThe basidiomycete Ustilago maydis causes smut disease in maize. Colonization of the host plant is initiated by direct penetration of cuticle and cell wall of maize epidermis cells. The invading hyphae are surrounded by...
- 8From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedBacterial pathogens are frequently distinguished by the presence of acquired genes associated with iron acquisition. The presence of specific siderophore receptor genes, however, does not reliably predict activity of the...
- 9From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedThe cytidine deaminases APOBEC3G and APOBEC3F exert anti-HIV-1 activity that is countered by the HIV-1 vif protein. Based on potential transcription factor binding sites in their putative promoters, we hypothesized that...
- 10From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedChronic immune activation and progression to AIDS are observed after SIV infection in macaques but not in natural host primate species. To better understand this dichotomy, we compared acute pathogenic SIV infection in...
- 11From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedThe genome of Trypanosoma brucei is unusual in being regulated almost entirely at the post-transcriptional level. In terms of regulation, the best-studied genes are procyclins, which encode a family of major surface...
- 12From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedOne of the most conserved features of the invasion process in Apicomplexa parasites is the formation of a moving junction (MJ) between the apex of the parasite and the host cell membrane that moves along the parasite and...
- 13From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedSimian immunodeficiency virus (SIV) infection leads to AIDS in experimentally infected macaques, whereas natural reservoir hosts exhibit limited disease and pathology. It is, however, unclear how natural hosts can...
- 14From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedEscherichia coli O157:H7 is a human enteric pathogen that causes hemorrhagic colitis which can progress to hemolytic uremic syndrome, a severe kidney disease with immune involvement. During infection, E. coli O157:H7...
- 15From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedModifications of the Plasmodium falciparum-infected red blood cell (iRBC) surface have been linked to parasite-associated pathology. Such modifications enable the parasite to establish long-lasting chronic infection by...
- 16From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedHuman neurons express the innate immune response receptor, Toll-like receptor 3 (TLR3). TLR3 levels are increased in pathological conditions such as brain virus infection. Here, we further investigated the production,...
- 17From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedInfection of red blood cells (RBC) subjects the malaria parasite to oxidative stress. Therefore, efficient antioxidant and redox systems are required to prevent damage by reactive oxygen species. Plasmodium spp. have...
- 18From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedPhthiocerol dimycocerosates (DIM) are major virulence factors of Mycobacterium tuberculosis (Mtb), in particular during the early step of infection when bacilli encounter their host macrophages. However, their cellular...
- 19From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedHuman papillomaviruses (HPVs) are DNA viruses associated with major human cancers. As such there is a strong interest in developing new means, such as vaccines and microbicides, to prevent HPV infections. Developing the...
- 20From: PLoS Pathogens. (Vol. 5, Issue 2) Peer-ReviewedRift Valley fever virus (RVFV) (genus Phlebovirus, family Bunyaviridae) is a negative-stranded RNA virus with a tripartite genome. RVFV is transmitted by mosquitoes and causes fever and severe hemorrhagic illness among...