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- Search Terms:ISSN: 15537366AndISSN: 15537374AndVolume Number: 5AndIssue Number: 1AndStart Page: e1000274AndDate: 2009 Revise Search
- 1From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedDespite considerable research efforts, little is yet known about key epidemiological parameters of H5N1 highly pathogenic influenza viruses in their avian hosts. Here we show how these parameters can be estimated using a...
- 2From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedCgPdr1 p is a Candida glabrata Zn(2)-Cys(6) transcription factor involved in the regulation of the ABC-transporter genes CgCDR1, CgCDR2, and CgSNQ2, which are mediators of azole resistance. Single-point mutations in...
- 3From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedSince 2003, more than 380 cases of H5N1 influenza virus infection of humans have been reported. Although the resultant disease in these cases was often severe or fatal, transmission of avian influenza viruses between...
- 4From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedSM1 is a twelve-amino-acid peptide that binds tightly to the Anopheles salivary gland and inhibits its invasion by Plasmodium sporozoites. By use of UV-crosslinking experiments between the peptide and its salivary gland...
- 5From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedLegionella pneumophila is an opportunistic pathogen that can cause a severe pneumonia called Legionnaires' disease. In the environment, L, pneumophila is found in fresh water reservoirs in a large spectrum of...
- 6From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedMechanisms by which viruses counter innate host defense responses generally involve inhibition of one or more components of the interferon (IFN) system. Multiple steps in the induction and amplification of IFN signaling...
- 7From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedArguments about the weaker sex notwithstanding, there is no contest about the identity of the sicker sex--it is males, almost every time. Everyone knows that old age homes have more widows than widowers, but the...
- 8From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedHorizontal gene transfer is a key step in the evolution of bacterial pathogens. Besides phages and plasmids, pathogenicity islands (PAIs) are subjected to horizontal transfer. The transfer mechanisms of PAIs within a...
- 9From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedThe final step during cell division is the separation of daughter cells, a process that requires the coordinated delivery and assembly of new membrane to the cleavage furrow. While most eukaryotic cells replicate by...
- 10From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedThe ubiquitous environmental human pathogen Cryptococcus neoformans is traditionally considered a haploid fungus with a bipolar mating system. In nature, the α mating type is overwhelmingly predominant over a. How...
- 11From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedInvasion of host cells by the malaria parasite involves recognition and interaction with cell-surface receptors. A wide variety of parasite surface proteins participate in this process, most of which are specific to the...
- 12From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedThe nuclear lamina is a major obstacle encountered by herpesvirus nucleocapsids in their passage from the nucleus to the cytoplasm (nuclear egress). We found that the human Cytomegalovirus (HCMV)-encoded protein kinase...
- 13From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedHost cell invasion by apicomplexan pathogens such as the malaria parasite Plasmodium spp. and Toxoplasma gondii involves discharge of proteins from secretory organelles called micronemes and rhoptries. In Toxoplasma a...
- 14From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedThe HIV promoter within the viral long terminal repeat (LTR) orchestrates many aspects of the viral life cycle, from the dynamics of viral gene expression and replication to the establishment of a latent state. In...
- 15From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedAlthough it has been known for 50 years that adenoviruses (Ads) interact with erythrocytes ex vivo, the molecular and structural basis for this interaction, which has been serendipitously exploited for diagnostic tests,...
- 16From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedEpstein-Barr virus (EBV) is a human herpesvirus that persists as a largely subclinical infection in the vast majority of adults worldwide. Recent evidence indicates that an important component of the persistence strategy...
- 17From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedFrancisella tularensis is a highly infectious bacterium causing the zoonotic disease tularemia. Its ability to multiply and survive in macrophages is critical for its virulence. By screening a bank of HimarFT transposon...
- 18From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedShigella, the causative agent of bacillary dysentery, invades epithelial cells by locally reorganizing the actin cytoskeleton. Shigella invasion requires actin polymerization dependent on the Src tyrosine kinase and a...
- 19From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedFilamentous fungi rely heavily on the secretory pathway, both for the delivery of cell wall components to the hyphal tip and the production and secretion of extracellular hydrolytic enzymes needed to support growth on...
- 20From: PLoS Pathogens. (Vol. 5, Issue 1) Peer-ReviewedPhage therapy is the use of bacteriophages as antimicrobial agents for the control of pathogenic and other problem bacteria. It has previously been argued that successful application of phage therapy requires a good...