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- 1From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedIn mice performing an operant task, increases in neural activity in direct- and indirect-pathway spiny projection neurons (SPNs) are associated with action initiation but not with inactivity, and concurrent activation of...
- 2From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedAgainst an epidemic of false, biased and falsified findings, the scientific community's defences are weak. Only the most egregious cases of misconduct are discovered and punished. Subtler forms slip through the net, and...
- 3From: Nature. (Vol. 494, Issue 7436) Peer-Reviewed14-18 FEBRUARY The American Association for the Advancement of Science holds its annual meeting in Boston, Massachusetts. www.aaas.org/meetings 19 FEBRUARY The US Supreme Court hears arguments in Bowman v....
- 4From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedA table in the Outlook article 'Nanotechnology: Carrying drugs' (Nature 491 (suppl. 7425), S58-S60; 2012) wrongly stated that Cerulean Pharma's drug CRLX101 is in phase I trials. In fact, it has been in phase II trials...
- 5From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedThe ambitious vision for Europe's next research programme dimmed last week when heads of the 27 member states of the European Union (EU) agreed to slash the overall budget for 2014-20, at the end of a long and...
- 6From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedG-protein-coupled receptors (GPCRs) are physiologically important membrane proteins that sense signalling molecules such as hormones and neurotransmitters, and are the targets of several prescribed drugs. Recent...
- 7From: Nature. (Vol. 494, Issue 7436) Peer-Reviewed$3.25 bn The amount, plus royalties, promised by Biogen Idec, a drug company in Weston, Massachusetts, for all rights to Tysabri, a multiple-sclerosis drug developed by Elan in Dublin. Sales of Tysabri were worth...
- 8From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedSubra Suresh, director of the US National Science Foundation (NSF), announced his resignation on 5 February, cutting short a six-year term after less than three years. He will leave the basic-research agency in late...
- 9From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedTo the eco-engineer, the glass is neither half-full nor half-empty. It is simply twice as big as it needs to be. Building with maximum efficiency and minimal materials is increasingly urgent in our resource-strapped...
- 10From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedFor many traits, including susceptibility to common diseases in humans, causal loci uncovered by genetic-mapping studies explain only a minority of the heritable contribution to trait variation. Multiple explanations...
- 11From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedGlucose production by the liver is essential for providing a substrate for the brain during fasting. The inability of insulin to suppress hepatic glucose output is a major aetiological factor in the hyperglycaemia of...
- 12From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedResearchers have found live microbes in water and sediment samples taken from Lake Whillans, a small body of water buried 800 metres beneath Antarctic ice. If the findings, confirmed to Nature on 10 February, hold up,...
- 13From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedHeather Piwowar lists several funders, including the UK Medical Research Council (MRC), that "still explicitly ask for a list of research papers rather than products" in their grant-application process (Nature 493, 159;...
- 14From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedVascular patterning is critical for organ function. In the eye, there is simultaneous regression of embryonic hyaloid vasculature (1) (important to clear the optical path) and formation of the retinal vasculature (2)...
- 15From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedControlled explosions make rubbery robot jump go.nature.com/I8395v...
- 16From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedGunmen burst into two clinics in the northern Nigerian city of Kano on 8 February and killed at least nine people, including polio-vaccination workers. No one has claimed responsibility, but the militant Islamist group...
- 17From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedThe trap that the US Congress devised two years ago to force cuts in the federal deficit is about to spring. Steep budget cuts, known as sequestration, are scheduled to hit on 1 March. In January, a deadlocked Congress...
- 18From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedIn his discussion of suspects in the Piltdown Man mystery, Chris Stringer alludes to the French Jesuit priest, philosopher and palaeontologist Pierre Teilhard de Chardin (Nature 492, 177-179; 2012). The article...
- 19From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedNASA launched the United States' latest Earth-observing satellite, Landsat 8, from Vandenberg Air Force Base in California on 11 February. The satellite is due to begin operations within 90 days, and will extend and...
- 20From: Nature. (Vol. 494, Issue 7436) Peer-ReviewedAsteroid 4 Vesta seems to be a major intact protoplanet, with a surface composition similar to that of the HED (howardite-eucrite-diogenite) meteorites (1-4). The southern hemisphere is dominated by a giant impact scar...