Showing Results for
- Academic Journals (30)
Search Results
- 30
Academic Journals
- 30
- Search Terms:
- 1From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedMacrophages engulf apoptotic cells to prevent immune responses to self antigens. In Nature Medicine, Chawla and colleagues show that PPAR-[delta], a sensor of fatty acids, is essential for efficient macrophage...
- 2From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedPrimary sclerosing cholangitis (PSC) is a chronic bile duct disease affecting 2.4-7.5% of individuals with inflammatory bowel disease. We performed a genome-wide association analysis of 2,466,182 SN Ps in 715...
- 3From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedForkhead box O (FOXO) transcription factors have been implicated in the regulation of aging in many organisms; for example, FOXO overexpression in the Drosophila fat body extends life span. Now, Fabio Demontis and...
- 4From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedData tables are a central element of most scientific papers. Simplified tables with separation of data storage from presentation format are ways to increase the impact and use of research data. (On the table) Datasets...
- 5From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedIn yeast, SIR2 is required for lifespan extension caused by caloric restriction. The sirtuin family of proteins has also been associated with metabolic regulation and stress tolerance, although it is not clear whether...
- 6From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedFunctional impairment of DNA damage response pathways leads to increased genomic instability. Here we describe the centrosomal protein CEP152 as a new regulator of genomic integrity and cellular response to DNA damage....
- 7From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedVernalization is the process by which plants acquire the ability to flower rapidly following exposure to prolonged cold temperatures. In Arabidopsis, this process involves stable silencing of the floral repressor FLC by...
- 8From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedPrimary ciliary dyskinesia (PCD) is a genetically heterogeneous autosomal recessive disorder characterized by recurrent infections of the respiratory tract associated with the abnormal function of motile cilia....
- 9From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedViral dissemination requires the release of newly synthesized virions from hijacked cells. In Cell, Bieniasz and colleagues report how tetherin, an interferon-inducible protein, blocks the release of HIV and other...
- 10From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedEndometriosis is a common gynecological disease associated with pelvic pain and subfertility. We conducted a genome-wide association study (GWAS) in 3,194 individuals with surgically confirmed endometriosis (cases) and...
- 11From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedAdult stem cells play pivotal roles in self-renewing tissues but also in the post-injury repair of adult organs that normally show little proliferative activity. a new study shows that Sox9 marks a putative adult stem...
- 12From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedCTL-mediated target cell killing requires polarization of the microtubule-organizing center (MTOC) and cytotoxic granules toward the target cell interface. In Immunity, groups led by Griffiths and Sykulev shed light on...
- 13From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedTo the Editor: McMahon and colleagues (1) recently reported a genome-wide significant association of rs2251219 on chromosome 3p21.1 with mood disorders in a combined sample of individuals with bipolar affective...
- 14From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedThe larvacean tunicate Oikopleura dioica lives in the open sea and displays chordate morphology. Daniel Chourrout, Patrick Wincker and colleagues now report sequencing of its 70 Mb genome (Science 330, 1381-1385, 2010)....
- 15From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedWe identified a deletion of a gene encoding a subunit of RNA polymerases I and III, POLR1D, in an individual with Treacher Collins syndrome (TCS). Subsequently, we detected 20 additional heterozygous mutations of POLR1D...
- 16From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedChronic or unresolved inflammation can lead to tissue damage or, during sepsis, to death. In Nature, Serhan and colleagues characterize a potent anti-inflammatory molecule, resolvin D2, which is naturally produced by...
- 17From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedPolycystic ovary syndrome (PCOS) is a common metabolic disorder in women. To identify causative genes, we conducted a genome-wide association study (GWAS) of PCOS in Han Chinese. The discovery set included 744 PCOS...
- 18From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedIn 1976, Bjorn Afzelius (1) startled researchers working in the cilia field by showing that ciliary assembly defects were responsible for Kartagener syndrome, which is characterized by sinusitis, bronchiectasis and...
- 19From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedThe liver and exocrine pancreas share a common structure, with functioning units (hepatic plates and pancreatic acini) connected to the ductal tree. Here we show that Sox9 is expressed throughout the biliary and...
- 20From: Nature Genetics. (Vol. 43, Issue 1) Peer-ReviewedWe conducted a two-stage genome-wide association study of renal cell carcinoma (RCC) in 3,772 affected individuals (cases) and 8,505 controls of European background from 11 studies and followed up 6 SNPs in 3...