Showing Results for
- Academic Journals (28)
Search Results
- 28
Academic Journals
- 28
- Search Terms:
- 1From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedIn a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC) (1), we describe here several new susceptibility variants. SNP rs11170164, encoding a G1 38E substitution in...
- 2From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedCongenital dyserythropoietic anemias (CDAs) are phenotypically and genotypically heterogeneous diseases (1-4). CDA type II (CDAII) is the most frequent CDA. It is characterized by ineffective erythropoiesis and by the...
- 3From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedA large cis-regulatory landscape is a common feature of vertebrate genomes, particularly at key developmental gene loci with finely tuned expression patterns. Existing genetic tools for surveying large genomic regions of...
- 4From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedA new study reports the first mouse model for ATR-mutated seckel syndrome. The mice show phenotypes recapitulating the human disorder and provide insights into how reduced aTR function affects normal embryonic...
- 5From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedTo understand how chromatin structure is organized by different histone variants, we have measured the genome-wide distribution of nucleosome core particles (NCPs) containing the histone variants H3.3 and H2A.Z in human...
- 6From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedTo identify risk variants for glioma, we conducted a meta-analysis of two genome-wide association studies by genotyping 550K tagging SNPs in a total of 1,878 cases and 3,670 controls, with validation in three additional...
- 7From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedWe conducted meta-analyses of genome-wide association studies for atrial fibrillation (AF) in participants from five community-based cohorts. Meta-analyses of 896 prevalent (15,768 referents) and 2,517 incident (21,337...
- 8From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedKidney stone disease is a common condition. To search for sequence variants conferring risk of kidney stones, we conducted a genome-wide association study in 3,773 cases and 42,510 controls from Iceland and The...
- 9From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedWe report a genome-wide association study of melanoma conducted by the GenoMEL consortium based on 317K tagging SNPs for 1,650 selected cases and 4,336 controls, with replication in an additional two cohorts (1,149...
- 10From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedWe conducted genome-wide association studies of non-Hodgkin lymphoma using Illumina HumanHap550 BeadChips to identify subtype-specific associations in follicular, diffuse large B-cell and chronic lymphocytic...
- 11From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedChromatin marks, including histone modifications and variants, have become important tools for characterizing epigenomes, yet how they might interact with one another to facilitate gene expression and regulation has...
- 12From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedAnatolia boasts over 9,000 years of complex and continuous civilization and stands at the point connecting Europe, Asia and the Middle East. Modern Turkey offers great opportunities for understanding the human genome,...
- 13From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedIn the version of this article initially published online, the name of author H.-Erich Wichmann was incorrectly given as Hans-E. Wichmann and this author's affiliation at the Institute of Medical Informatics, Biometry...
- 14From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedIn the version of this article initially published online, there were two errors in the author affiliations. For footnote 3, the correct affiliation is "Service de Neurologie Mazarin and UNIR 975 INSERM-UPMC, GH...
- 15From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedTo the Editor: In a recent Nature Genetics letter, Benko et al. (1) describe a series of changes in noncoding elements 5' and 3' of SOX9 in individuals with Pierre Robin sequence, a condition characterized by...
- 16From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedHomozygosity for the G allele of rs6983267 at 8q24 increases colorectal cancer (CRC) risk B1.5 fold. We report here that the risk allele G shows copy number increase during CRC development. Our computer algorithm,...
- 17From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedTetralogy of Fallot (TOF), the most common severe congenital heart malformation, occurs sporadically, without other anomaly, and from unknown cause in 70% of cases. Through a genome-wide survey of 114 subjects with TOF...
- 18From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedLung adenocarcinomas are able to rapidly metastasize. Joan Massague and colleagues report that hyperactive WNT/TCF signaling mediates the metastatic capability of these tumors (Cell 138, 51-62; 2009). The authors...
- 19From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedAlthough DNA damage is considered a driving force for aging, the nature of the damage that arises endogenously remains unclear. Replicative stress, a source of endogenous DNA damage, is prevented primarily by the ATR...
- 20From: Nature Genetics. (Vol. 41, Issue 8) Peer-ReviewedWe expanded our genome-wide association study on atrial fibrillation (AF) in Iceland, which previously identified risk variants on 4g25, and tested the most significant associations in samples from Iceland, Norway and...