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- Search Terms:ISSN: 15491277AndISSN: 15491676AndVolume Number: 4AndIssue Number: 8AndStart Page: e261AndDate: 2007 Revise Search
- 1From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedABSTRACT Background Treatment recommendations for the same condition from different guideline bodies often disagree, even when the same randomized controlled trial (RCT) evidence is cited. Guideline appraisal tools...
- 2From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedABSTRACT Background The importance of understanding age when estimating the impact of influenza on hospitalizations and deaths has been well described, yet existing surveillance systems have not made adequate use of...
- 3From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedABSTRACT Background Clinical trials of interventions designed to prevent severe falciparum malaria in children require a clear endpoint. The internationally accepted definition of severe malaria is sensitive, and...
- 4From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedIt may seem remarkable that, 23 years after the identification of the human immunodeficiency virus (HIV), there is still denial that the virus is the cause of acquired immune deficiency syndrome (AIDS). This denial was...
- 5From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedThe lack of a "gold standard" definition for severe malaria has been a longstanding problem for both clinicians and researchers. The definitions currently used comprise a set of clinical and laboratory parameters...
- 6From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedABSTRACT Background Control of body weight by balancing energy intake and energy expenditure is of major importance for the prevention of type 2 diabetes, but the role of specific dietary factors in the etiology of...
- 7From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedSummary Points * Regulatory authorities from developing countries should be actively engaged in both product and clinical review of TB vaccines being investigated within their nation. * In order to generate data that...
- 8From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedBackground Understanding the mechanisms of amyloid-β protein (Aβ) production and clearance in the brain has been essential to elucidating the etiology of Alzheimer disease (AD). Chronically decreasing brain Aβ levels...
- 9From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedThe world's neglected tropical diseases (NTDs; Table 1) are becoming less neglected. Many millions of dollars and drugs are now committed to their control, and an open-access journal dedicated to NTDs, PLoS Neglected...
- 10From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedThere have been significant increases in development finance since 2000, particularly for health [1,2]. As country programs put this money to work, important lessons and challenges on how to make health finance more...
- 11From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedFIVE KEY PAPERS IN THE FIELD Van den Akker-van Marle et al., 2006 [26] Provides evidence that TPMT genotyping prior to thiopurine treatment initation is cost effective in children with acute lymphoblastic leukemia....
- 12From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedABSTRACT Background Highly active antiretroviral treatment (HAART) has only been recently recommended for HIV-infected pregnant women requiring treatment for their own health in resource-limited settings. However,...
- 13From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedEvidence-based medicine requires that clinical decisions be consistent not only with the best available research evidence, but with the values and preferences of the informed patient [1]. To achieve this goal, clinicians...
- 14From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedSummary Points * This paper aims to define health research priorities in South Africa, where it is estimated that nearly 100,000 children under 5 years of age still die each year. * The authors applied the...
- 15From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedABSTRACT Background Evidence suggests that variations in fasting glucose and insulin amongst those without frank type 2 diabetes mellitus are important determinants of cardiovascular disease. However, the relative...
- 16From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedABSTRACT Background Langerhans cell histiocytosis (LCH) is a rare clonal granulomatous disease that affects mainly children. LCH can involve various tissues such as bone, skin, lung, bone marrow, lymph nodes, and the...
- 17From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedABSTRACT Background Inexpensive and efficacious interventions that avert childhood deaths in sub-Saharan Africa have failed to reach effective coverage, especially among the poorest rural sectors. One particular...
- 18From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedWhy do up to half of all patients with tuberculosis (TB) fail to adhere to drug treatment [1]? The answer to this question is a matter of life and death, since nonadherence contributes to disease relapse and mortality...
- 19From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedCorrection for: Shir A, Ogris M, Wagner E, Levitzki A (2006) EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice. PLoS Med 3(l): e6....
- 20From: PLoS Medicine. (Vol. 4, Issue 8) Peer-ReviewedCorrection for: Kuntz AN, Davioud-Charvet E, Sayed AA, Califf LL, Dessolin J, et al. (2007) Thioredoxin Glutathione Reductase from Schistosorna mansonk An Essential Parasite Enzyme and a Key Drug Target. PLoS Med...