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- 1From: PLoS Pathogens. (Vol. 4, Issue 7) Peer-ReviewedImmunity to the murine cytomegalovirus (MCMV) is critically dependent on the innate response for initial containment of viral replication, resolution of active infection, and proper induction of the adaptive phase of...
- 2From: PLoS Pathogens. (Vol. 4, Issue 7) Peer-ReviewedDrosophila melanogaster mount an effective innate immune response against invading microorganisms, but can eventually succumb to persistent pathogenic infections. Understanding of this pathogenesis is limited, but it...
- 3From: PLoS Pathogens. (Vol. 4, Issue 7) Peer-ReviewedHere, we describe the generation of a novel type of HIV entry inhibitor using the recently developed Designed Ankyrin Repeat Protein (DARPin) technology. DARPin proteins specific for human CD4 were selected from a...
- 4From: PLoS Pathogens. (Vol. 4, Issue 7) Peer-ReviewedThe sensing of pathogen infection and subsequent triggering of innate immunity are key to controlling zoonotic infections. Myxoma virus (MV) is a cytoplasmic DNA poxvirus that in nature infects only rabbits. Our...
- 5From: PLoS Pathogens. (Vol. 4, Issue 7) Peer-ReviewedEncounters with pathogens provoke changes in gene transcription that are an integral part of host innate immune responses. In recent years, studies with invertebrate model organisms have given insights into the origin,...
- 6From: PLoS Pathogens. (Vol. 4, Issue 7) Peer-ReviewedSurveillance of the antiviral susceptibility of influenza viruses in Europe revealed the emergence of influenza A(H1N1) viruses naturally resistant to the anti-neuraminidase inhibitor oseltamivir (Tamiflu) [1]....
- 7From: PLoS Pathogens. (Vol. 4, Issue 7) Peer-ReviewedRecent data suggest that Nef-mediated downmodulation of TCR-CD3 may protect SIVsmm-infected sooty mangabeys (SMs) against the loss of [CD4.sup.+] T cells. However, the mechanisms underlying this protective effect remain...
- 8From: PLoS Pathogens. (Vol. 4, Issue 7) Peer-ReviewedNoroviruses are important human pathogens responsible for most cases of viral epidemic gastroenteritis worldwide. Murine norovirus-1 (MNV-1) is one of several murine noroviruses isolated from research mouse facilities...
- 9From: PLoS Pathogens. (Vol. 4, Issue 7) Peer-ReviewedBrucella species are facultative intracellular bacterial pathogens that cause brucellosis, a global zoonosis of profound importance. Although recent studies have demonstrated that Brucella spp. replicate within an...
- 10From: PLoS Pathogens. (Vol. 4, Issue 7) Peer-ReviewedThe bank vole is a rodent susceptible to different prion strains from humans and various animal species. We analyzed the transmission features of different prions in a panel of seven rodent species which showed various...