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- Search Terms:ISSN: 15537366AndISSN: 15537374AndVolume Number: 4AndIssue Number: 3AndStart Page: e1000021AndDate: 2008 Revise Search
- 1From: PLoS Pathogens. (Vol. 4, Issue 3) Peer-ReviewedInternalization of the pathogenic bacterium Pseudomonas aeruginosa by non-phagocytic cells is promoted by rearrangements of the actin cytoskeleton, but the host pathways usurped by this bacterium are not clearly...
- 2From: PLoS Pathogens. (Vol. 4, Issue 3) Peer-ReviewedInterferons (IFN) exert antiviral, immunomodulatory and cytostatic activities. IFN-[alpha]/[beta] (type I IFN) and IFN-[lambda] (type III IFN) bind distinct receptors, but regulate similar sets of genes and exhibit...
- 3From: PLoS Pathogens. (Vol. 4, Issue 3) Peer-ReviewedPersistent infection with the hepatitis C virus (HCV) is a major risk factor for the development of liver cirrhosis and hepatocellular carcinoma. With an estimated about 3% of the world population infected with this...
- 4From: PLoS Pathogens. (Vol. 4, Issue 3) Peer-ReviewedThe factors that govern the development of tuberculosis disease are incompletely understood. We hypothesized that some strains of Mycobacterium tuberculosis (M, tuberculosis) are more capable of causing disseminated...
- 5From: PLoS Pathogens. (Vol. 4, Issue 3) Peer-ReviewedThe opa genes of the Gram negative bacterium Neisseria meningitidis encode Opacity-associated outer membrane proteins whose role is to promote adhesion to the human host tissue during colonisation and invasion. Each...
- 6From: PLoS Pathogens. (Vol. 4, Issue 3) Peer-ReviewedPili have been identified on the cell surface of Streptococcus pneumoniae, a major cause of morbidity and mortality worldwide. In contrast to Gram-negative bacteria, little is known about the structure of native pili in...
- 7From: PLoS Pathogens. (Vol. 4, Issue 3) Peer-ReviewedHuman T-lymphotropic virus type 1 (HTLV-1) causes leukaemia or chronic inflammatory disease in ~5% of infected hosts. The level of proviral expression of HTLV-1 differs significantly among infected people, even at the...
- 8From: PLoS Pathogens. (Vol. 4, Issue 3) Peer-ReviewedRetroviral replication proceeds through a stable proviral DNA intermediate, and numerous host cell factors have been implicated in its formation. In particular, recent results have highlighted an important role for the...
- 9From: PLoS Pathogens. (Vol. 4, Issue 3) Peer-ReviewedHepatitis C virus (HCV) is a significant pathogen, infecting some 170 million people worldwide. Persistent virus infection often leads to cirrhosis and liver cancer. In the infected cell many RNA directed processes must...
- 10From: PLoS Pathogens. (Vol. 4, Issue 3) Peer-ReviewedOne of the most important genetic factors known to affect the rate of disease progression in HIV-infected individuals is the genotype at the Class I Human Leukocyte Antigen (HLA) locus, which determines the HIV peptides...