Showing Results for
- Academic Journals (31)
Search Results
- 31
Academic Journals
- 31
- Search Terms:ISSN: 15537390AndISSN: 15537404AndVolume Number: 4AndIssue Number: 12AndStart Page: e1000301AndDate: 2008 Revise Search
- 1From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedVariation in gene expression is a fundamental aspect of human phenotypic variation. Several recent studies have analyzed gene expression levels in populations of different continental ancestry and reported population...
- 2From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedDosage compensation in male Drosophila relies on the X chromosome--specific recruitment of a chromatin-modifying machinery, the dosage compensation complex (DCC). The principles that assure selective targeting of the...
- 3From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedMetanephric kidney induction critically depends on mesenchymal-epithelial interactions in the caudal region of the nephric (or Wolffian) duct. Central to this process, GDNF secreted from the metanephric mesenchyme...
- 4From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedBacterial chromosomes are organised as two replichores of opposite polarity that coincide with the replication arms from the ori to the ter region. Here, we investigated the effects of asymmetry in replichore...
- 5From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedUsing the genomic sequences of Drosophila melanogaster subgroup, the pattern of gene duplications was investigated with special attention to interlocus gene conversion. Our fine-scale analysis with careful visual...
- 6From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedI once had a post-doctoral fellow who, upon discovering we had grown up a quarter mile from each other in a small town in Pennsylvania, commented on our shared experience with, "Well, you know what they say about...
- 7From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedThe bacterial stringent response, triggered by nutritional deprivation, causes an accumulation of the signaling nucleotides pppGpp and ppGpp. We characterize the replication arrest that occurs during the stringent...
- 8From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedEndogenous 24 nt short interfering RNAs (siRNAs), derived mostly from intergenic and repetitive genomic regions, constitute a major class of endogenous small RNAs in flowering plants. Accumulation of Arabidopsis...
- 9From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedShikimate kinase (SK; EC 2.7.1.71) catalyzes the fifth reaction of the shikimate pathway, which directs carbon from the central metabolism pool to a broad range of secondary metabolites involved in plant development,...
- 10From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedIn women, oocytes arrest development at the end of prophase of meiosis I and remain quiescent for years. Over time, the quality and quantity of these oocytes decreases, resulting in fewer pregnancies and an increased...
- 11From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedThe experimental evolution of laboratory populations of microbes provides an opportunity to observe the evolutionary dynamics of adaptation in real time. Until very recently, however, such studies have been limited by...
- 12From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedIn many mammalian neurons, dense clusters of ion channels at the axonal initial segment and nodes of Ranvier underlie action potential generation and rapid conduction. Axonal clustering of mammalian voltage-gated sodium...
- 13From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedKindler Syndrome (KS), characterized by transient skin blistering followed by abnormal pigmentation, skin atrophy, and skin cancer, is caused by mutations in the FERMT1 gene. Although a few KS patients have been...
- 14From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedWe have experimentally and computationally defined a set of genes that form a conserved metabolic module in the aproteobacterium Caulobacter crescentus and used this module to illustrate a schema for the propagation of...
- 15From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedTwo articles published in this issue of PLoS Genetics present novel data concerning the members of a key regulator of genetic crossing-over. Working with the plant Arabidopsis thaliana, the authors of the two reports...
- 16From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedMelanin protects the skin and eyes from the harmful effects of UV irradiation, protects neural cells from toxic insults, and is required for sound conduction in the inner ear. Aberrant regulation of melanogenesis...
- 17From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedWe have exploited the high selectivity of the homing endonuclease I-PpoI for the X-linked Anopheles gambiae 28S ribosomal genes to selectively target X chromosome carrying spermatozoa. Our data demonstrated that in...
- 18From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedGenomic conflict is perplexing because it causes the fitness of a species to decline rather than improve. Many diverse forms of genomic conflict have been identified, but this extant tally may be incomplete. Here, we...
- 19From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedA complete description of the transcriptome of an organism is crucial for a comprehensive understanding of how it functions and how its transcriptional networks are controlled, and may provide insights into the...
- 20From: PLoS Genetics. (Vol. 4, Issue 12) Peer-ReviewedTopoisomerases are enzymes with crucial functions in DNA metabolism. They are ubiquitously present in prokaryotes and eukaryotes and modify the steady-state level of DNA supercoiling. Biochemical analyses indicate that...