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- 7,247
Academic Journals
- 7,247
- Search Terms:ISSN: 10614036AndISSN: 15461718AndVolume Number: 38 SupplAndStart Page: S2AndDate: 2006 Revise Search
- 1From: Nature Genetics. (Vol. 52, Issue 6) Peer-ReviewedOne of the many consequences of the global COVID-19 pandemic is the need for the scientific community to adapt to the cancellation of conferences and events because of travel restrictions and social-distancing...
- 2From: Nature Genetics. (Vol. 51, Issue 10) Peer-ReviewedA hallmark of the immune system is the interplay among specialized cell types transitioning between resting and stimulated states. The gene regulatory landscape of this dynamic system has not been fully characterized in...
- 3From: Nature Genetics. (Vol. 46, Issue 7) Peer-ReviewedFrançois Spitz and colleagues identify cis-acting enhancers of Myc in a region orthologous to human 8q24 that are required for normal development of the face in mice. Their results shed light on the role of this region...
- 4From: Nature Genetics. (Vol. 52, Issue 5) Peer-ReviewedGenome-wide association studies have discovered hundreds of loci associated with complex brain disorders, but it remains unclear in which cell types these loci are active. Here we integrate genome-wide association study...
- 5From: Nature Genetics. (Vol. 46, Issue 9) Peer-ReviewedTrey Ideker and colleagues report a comprehensive genome-wide analysis of head and neck squamous cell carcinoma, reporting that TP53 mutations are frequently accompanied by loss of chromosome 3p. Their data indicate that...
- 6From: Nature Genetics. (Vol. 52, Issue 1) Peer-ReviewedR-loops are nucleic acid structures formed by an RNA:DNA hybrid and unpaired single-stranded DNA that represent a source of genomic instability in mammalian cells.sup.1-4. Here we show that N.sup.6-methyladenosine...
- 7From: Nature Genetics. (Vol. 46, Issue 9) Peer-ReviewedRama Khokha and colleagues report a new mutagenesis method, called Lentihop, for creating spontaneous, genetically tractable tumors from normal human cells. Through genetic analysis of Lentihop-derived tumors, they find...
- 8From: Nature Genetics. (Vol. 48, Issue 1) Peer-ReviewedAuthor(s): Zheng Hu 1 , Da Zhu 1 , Wei Wang 2 , Weiyang Li 3 4 , Wenlong Jia 3 5 , Xi Zeng 3 , Xun Xu 3 , Hui Wang 1 , Ding Ma 1 Author Affiliations: (1) Department of Obstetrics and Gynecology, Tongji Hospital,...
- 9From: Nature Genetics. (Vol. 52, Issue 9) Peer-ReviewedMost cancer genomic data are generated from bulk samples composed of mixtures of cancer subpopulations, as well as normal cells. Subclonal reconstruction methods based on machine learning aim to separate those...
- 10From: Nature Genetics. (Vol. 43, Issue 11) Peer-ReviewedAuthor(s): Pamela Feliciano Author Affiliations: Cancer has typically been thought of as a linear disease, with metastasis occurring as a late event. However, a few studies suggest that cancer cell dissemination can...
- 11From: Nature Genetics. (Vol. 39, Issue 2) Peer-ReviewedAuthor(s): Alan Herbert 1, Marc E Lenburg 1, David Ulrich 2, Norman P Gerry 1, Karen Schlauch 1, Michael F Christman 1 Author Affiliations: (1) Department of Genetics and Genomics, Boston University School of...
- 12From: Nature Genetics. (Vol. 52, Issue 8) Peer-ReviewedGenomes are highly organized in space and time. Compartments, topologically associating domains (TADs) and loops are three dimensional (3D) genome features that have been extensively studied. Among these three levels of...
- 13From: Nature Genetics. (Vol. 52, Issue 10) Peer-ReviewedCancers accumulate mutations that lead to neoantigens, novel peptides that elicit an immune response, and consequently undergo evolutionary selection. Here we establish how negative selection shapes the clonality of...
- 14From: Nature Genetics. (Vol. 52, Issue 10) Peer-ReviewedAccess to medical data is central for conducting research on genomics. However, to tap these metadata (observable traits and phenotypes, diagnoses and medication, and labels), researchers must grapple with the complex...
- 15From: Nature Genetics. (Vol. 53, Issue 2) Peer-ReviewedAn amendment to this paper has been published and can be accessed via a link at the top of the paper. Author(s): Mark K. Bakker 1 , Rick A. A. van der Spek 1 , Wouter van Rheenen 1 , Sandrine Morel 2 3 , Romain...
- 16From: Nature Genetics. (Vol. 53, Issue 5) Peer-ReviewedMost eukaryotes harbor two distinct pre-mRNA splicing machineries: the major spliceosome, which removes >99% of introns, and the minor spliceosome, which removes rare, evolutionarily conserved introns. Although...
- 17From: Nature Genetics. (Vol. 53, Issue 6) Peer-ReviewedLarge-scale genomic surveys of crop germplasm are important for understanding the genetic architecture of favorable traits. The genomic basis of geographic differentiation and fiber improvement in cultivated cotton is...
- 18From: Nature Genetics. (Vol. 53, Issue 5) Peer-ReviewedDinoflagellate chromosomes represent a unique evolutionary experiment, as they exist in a permanently condensed, liquid crystalline state; are not packaged by histones; and contain genes organized into tandem gene...
- 19From: Nature Genetics. (Vol. 53, Issue 4) Peer-ReviewedThe structure of chromatin is associated with its function, but precisely how is unclear. New data show that the higher-order architecture of the genome is similar among cell types with widely variant fates and gene...
- 20From: Nature Genetics. (Vol. 53, Issue 7) Peer-ReviewedMitochondrial DNA (mtDNA) variation in common diseases has been underexplored, partly due to a lack of genotype calling and quality-control procedures. Developing an at-scale workflow for mtDNA variant analyses, we show...