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- 1From: Journal of Psychiatry and Neuroscience. (Vol. 32, Issue 5) Peer-ReviewedObjective: Investigators have reported that weight gain attributed to clozapine is associated with its clinical response. However, weight gain is a nonspecific physiological variable that, in itself, does not explain the...
- 2From: Journal of Psychiatry and Neuroscience. (Vol. 32, Issue 5) Peer-ReviewedObjective: Cholesterol levels have been reported to be lower in suicidal patients, and alterations in blood levels of polyunsaturated fatty acids have been found in people with depression. Given that the evidence for the...
- 3From: Journal of Psychiatry and Neuroscience. (Vol. 32, Issue 5) Peer-ReviewedBackground: Patients with major depressive disorder (MDD) show impairments in cognitive functions. However, neural mechanisms underlying these disturbances are poorly understood. We investigated whether MDD affects...
- 4From: Journal of Psychiatry and Neuroscience. (Vol. 32, Issue 5) Peer-ReviewedIntroduction: Auditory sensory processing dysfunction is a core component of schizophrenia, with deficits occurring at 50 ms post-stimulus firmly established in the literature. Given that the initial afference of primary...
- 5From: Journal of Psychiatry and Neuroscience. (Vol. 32, Issue 5) Peer-ReviewedAlthough monoamine oxidase (MAO) inhibitors are not used as extensively as other antidepressants, they continue to have an important place in the armamentarium of drugs used to treat psychiatric and neurological...
- 6From: Journal of Psychiatry and Neuroscience. (Vol. 32, Issue 5) Peer-ReviewedObjective: The antipsychotic drug haloperidol (HAL) has been linked to apoptosis and to inhibition of prosurvival Akt signalling in pheochromocytoma (PC12) and neuronal cell cultures. However, the mechanism involved is...
- 7From: Journal of Psychiatry and Neuroscience. (Vol. 32, Issue 5) Peer-ReviewedA 60-year-old man with left-sided limb weakness after a stroke was referred for assessment and treatment of depression. The patient reported that, after his stroke 2 weeks ago, he has been crying "for no reason" several...
- 8From: Journal of Psychiatry and Neuroscience. (Vol. 32, Issue 5) Peer-ReviewedBackground: Low-function alleles of the serotonin transporter promoter polymorphism (5HTTLPR) have been linked to various psychopathological entities, especially in individuals exposed to prior stressors. In women with...