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- 1From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedMultidrug-resistant tuberculosis (MDR-TB) is on the increase, with several Eastern European countries having a prevalence of more than ten percent [1]. This resistance means that patients may not be cured with standard...
- 2From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedABSTRACT Background Celiac disease is a small intestine inflammatory disorder with multiple organ involvement, sustained by an inappropriate immune response to dietary gluten. Anti-transglutaminase antibodies are a...
- 3From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedThe great burden that noncommunicable diseases (NCDs) and injuries have on low-income and middle-income countries is well recognized [1,2]. Latin American and Caribbean (LAC) countries as a group of middle-income...
- 4From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedThe Role of Reactive Oxygen Species For many years, reactive oxygen species (ROS), including superoxide, hydrogen peroxide, and hydroxyl radicals, and their reaction products, were classically described as harmful...
- 5From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedIn a study in PLoS Medicine, Murray and colleagues take a new look at health disparities using county-level data [1]. Their findings have implications for understanding the social geography of health and for setting...
- 6From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedABSTRACT Background Despite recent successes with biological agents as therapy for autoimmune inflammatory diseases such as rheumatoid arthritis (RA), many patients fail to respond adequately to these treatments,...
- 7From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedABSTRACT Background Multidrug-resistant tuberculosis (MDR-TB) is an important global health problem, and a control strategy known as DOTS-Plus has existed since 1999. However, evidence regarding the feasibility,...
- 8From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedABSTRACT Background The gap between the highest and lowest life expectancies for race-county combinations in the United States is over 35 y. We divided the race-county combinations of the US population into eight...
- 9From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedABSTRACT Background The outbreak of highly pathogenic H5N1 influenza in domestic poultry and wild birds has caused global concern over the possible evolution of a novel human strain [1]. If such a strain emerges, and...
- 10From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedABSTRACT Background Somatic afferent input to the spinal cord from a peripheral inflammatory site can modulate the peripheral response. However, the intracellular signaling mechanisms in the spinal cord that regulate...
- 11From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedDESCRIPTION of CASE The patient, a two-month-old Gambian infant, was one of twins born in November 2003. In the latter part of her pregnancy, the patient's mother went to stay with her family in southern Senegal, where...
- 12From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedIn recent years, highly pathogenic avian influenza A viruses of the H5N1 subtype have crossed the species barrier and infected humans in many parts of the world. These strains continue to evolve and expand their host...
- 13From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedBackground to the debate: Uganda is one of the few African countries where rates of HIV infection have fallen, from about 15 percent in the early 1990s to about five percent in 2001. At the end of 2005, UNAIDS estimated...
- 14From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedAcademic medicine occupies a spot in that rarefied world in which one doesn't have to do much to justify one's existence. The best health care, the best research, the brightest minds on the planet circulate within...
- 15From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedDuring the past 20 years, natural disasters have claimed more than 3 million lives worldwide, affected at least 800 million people, and resulted in property damage exceeding $US50 billion [1]. On 8 October 2005, an...
- 16From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedABSTRACT Background Data on birth outcome and offspring health after the appearance of breast cancer are limited. The aim of this study was to assess the risk of adverse birth outcomes in women previously treated for...
- 17From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedABSTRACT Background The burden of shigellosis is greatest in resource-poor countries. Although this diarrheal disease has been thought to cause considerable morbidity and mortality in excess of 1,000,000 deaths...
- 18From: PLoS Medicine. (Vol. 3, Issue 9) Peer-Reviewed"The accomplishments of this Programme inspire all of us in public health to dream big dreams. It shows we can reach 'impossible' goals and lighten the burden of millions of the world's poorest people...." These were the...
- 19From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedABSTRACT Background The SARS outbreak of 2002-2003 presented clinicians with a new, life-threatening disease for which they had no experience in treating and no research on the effectiveness of treatment options. The...
- 20From: PLoS Medicine. (Vol. 3, Issue 9) Peer-ReviewedABSTRACT Background Recent outbreaks of highly pathogenic influenza A H5N1 viruses in humans and avian species that began in Asia and have spread to other continents underscore an urgent need to develop vaccines that...