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- Search Terms:ISSN: 15537390AndISSN: 15537404AndVolume Number: 3AndIssue Number: 8AndStart Page: e145AndDate: 2007 Revise Search
- 1From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedIt frequently has been postulated that intersexual coevolution between the male ejaculate and the female reproductive tract is a driving force in the rapid evolution of reproductive proteins. The dearth of research on...
- 2From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedThe identification of regulatory elements from different cell types is necessary for understanding the mechanisms controlling cell type-specific and housekeeping gene expression. Mapping DNaseI hypersensitive (HS) sites...
- 3From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedFiltration usually eliminates water-living bacteria. Here, we report on the complete genome sequence of Minibacterium massiliensis, a β-proteobacteria that was recovered from 0.22-µm filtered water used for patients in...
- 4From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedPaternal repression of the imprinted H19 gene is mediated by a differentially methylated domain (DMD) that is essential to imprinting of both H19 and the linked and oppositely imprinted Igf2 gene. The mechanisms by which...
- 5From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedThe first reported Far East scarlet-like fever (FESLF) epidemic swept the Pacific coastal region of Russia in the late 1950s. Symptoms of the severe infection included erythematous skin rash and desquamation, exanthema,...
- 6From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedMUS81 is conserved among plants, animals, and fungi and is known to be involved in mitotic DNA damage repair and meiotic recombination. Here we present a functional characterization of the Arabidopsis thaliana homolog...
- 7From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedRetrotransposons are mobile genetic elements that proliferate through an RNA intermediate. Transposons do not encode transcription factors and thus rely on host factors for mRNA expression and survival. Despite...
- 8From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedCrossing over during meiotic prophase I is required for sexual reproduction in mice and contributes to genome-wide genetic diversity. Here we report on the characterization of an N-ethyl-N-nitrosourea-induced, recessive...
- 9From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedCytoplasmic dynein is a microtubule-dependent motor protein that functions in mitotic cells during centrosome separation, metaphase chromosome congression, anaphase spindle elongation, and chromosome segregation. Dynein...
- 10From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedGenomic aberrations recurrent in a particular cancer type can be important prognostic markers for tumor progression. Typically in early tumorigenesis, cells incur a breakdown of the DNA replication machinery that results...
- 11From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedHere we report that the change from the red seeds of wild rice to the white seeds of cultivated rice (Oryza sativa) resulted from the strong selective sweep of a single mutation, a frame-shift deletion within the Rc gene...
- 12From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedMeiotic recombination is initiated by DNA double-strand breaks (DSBs) made by Spo11 (Rec12 in fission yeast), which becomes covalently linked to the DSB ends. Like recombination events, DSBs occur at hotspots in the...
- 13From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedGenome instability is a hallmark of cancer cells. One class of genome aberrations prevalent in tumor cells is termed gross chromosomal rearrangements (GCRs). GCRs comprise chromosome translocations, amplifications,...
- 14From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedThe primitive heart tube is composed of an outer myocardial and an inner endocardial layer that will give rise to the cardiac valves and septa. Specification and differentiation of these two cell layers are among the...
- 15From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedIn mammalian meiosis, homologous chromosome synapsis is coupled with recombination. As in most eukaryotes, mammalian meiocytes have checkpoints that monitor the fidelity of these processes. We report that the mouse...
- 16From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedUnderstanding the transcriptional regulation of pluripotent cells is of fundamental interest and will greatly inform efforts aimed at directing differentiation of embryonic stem (ES) cells or reprogramming somatic cells....
- 17From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedABSTRACT The recent revelation that there are small, noncoding RNAs that regulate the expression of many other genes has led to an exciting, emerging body of literature defining the biological role for these molecules...
- 18From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedCrosses between laboratory strains of mice provide a powerful way of detecting quantitative trait loci for complex traits related to human disease. Hundreds of these loci have been detected, but only a small number of...
- 19From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedHow duplicate genes provide genetic robustness remains an unresolved question. We have examined the duplicated histone deacetylases Sir2p and Hst1p in Saccharomyces cerevisiae and find that these paralogs with...
- 20From: PLoS Genetics. (Vol. 3, Issue 8) Peer-ReviewedThe Huntington's disease (HD) CAG repeat, encoding a polymorphic glutamine tract in huntingtin, is inversely correlated with cellular energy level, with alleles over ~37 repeats leading to the loss of striatal neurons....