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- 1From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedAuthor(s): Brian Duerden (corresponding author) [1] The last 25 years of the twentieth century represented a paradox for medical microbiology. While microbiologists were driving the molecular and genomic revolution in...
- 2From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedRobert Koch (1843-1910) is one of the founding fathers of medical microbiology and is probably most well known for his guidelines for establishing a microorganism as the causative agent of an infectious disease. The...
- 3From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedAuthor(s): Nancy P. Keller [1]; Geoffrey Turner [2]; Joan W. Bennett [3] The fungal kingdom includes many species with unique and unusual biochemical pathways. The products of these pathways include important...
- 4From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedAuthor(s): Annie Tremp Viral infection induces an innate immune response in neurons, a group led by Monique Lafon at the Pasteur Institute in Paris, France, has found. It was previously thought that the nervous system...
- 5From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedAuthor(s): Carlos J. Paredes [1, 2]; Keith V. Alsaker [1, 2]; Eleftherios T. Papoutsakis (corresponding author) [1] The Gram-positive, anaerobic clostridia are non-sulphur-reducing rods that can form heat-stable...
- 6From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedAuthor(s): David O' Connell Microbiologists from Duke University have unraveled the story behind the emergence of a virulent fungus strain that was responsible for an 1999 outbreak of meningoencephalitis on Vancouver...
- 7From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedAuthor(s): Marilyn J. Roossinck [1] The Darwinian model of evolution by natural selection states that evolution is a gradual process of change that is produced by the accumulation of random mutations followed by...
- 8From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedMMR declared safe A comprehensive review of published studies on the measles, mumps and rubella (MMR) vaccine has concluded that there is "no credible evidence" that the vaccine is involved in Crohn's disease or...
- 9From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedTechniques and applications Defining genes in the genome of the hyperthermophilic archaeon Pyrococcus furiosus : implications for all microbial genomes Poole, F. L. II et al . J. Bacteriol. 187, 7325-7332 (2005)...
- 10From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedAuthor(s): Sheilagh Molloy In the 1918-1919 influenza pandemic, one-third of the world's population is believed to have been infected with the virus, and up to 50 million people died. Now, almost 90 years later, the...
- 11From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedAuthor(s): Joanna Owens [1] Hsp90 is well known for its role as a molecular chaperone -- a protein that assists the folding of other proteins ('clients'). Now, research published in Science reveals that Hsp90 might...
- 12From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedThis month's report from the microbial-genomics banquet dishes up new representatives for two genome-rich bacterial groups, along with a eukaryotic microorganism that consumes bacteria. The genome of Rickettsia felis is...
- 13From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedStaphylococcus aureus can cause superficial skin infections and, occasionally, deep-seated infections that entail spread through the blood stream. The organism expresses several factors that compromise the effectiveness...
- 14From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedMicrobial secondary metabolites represent some of the most useful and important molecules in human medicine. The fungal kingdom includes many species that produce secondary metabolites with important medicinal value,...
- 15From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedAuthor(s): Sharon Ahmad The pili of Gram-negative pathogens have important roles in virulence and protection, and their biology has been well characterized. Little is known, however, about the extended surface...
- 16From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedThe site of cell division in bacterial cells is placed with high fidelity at a designated position, usually the midpoint of the cell. In normal cell division in Escherichia coli this is accomplished by the action of the...
- 17From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedAuthor(s): Shannon Amoils Bacteria use chemical signals called autoinducers to communicate with one another -- a phenomenon known as quorum sensing. By producing and importing autoinducers, bacterial cells establish...
- 18From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedThe bacterial multienzyme polyketide synthases (PKSs) produce a diverse array of products that have been developed into medicines, including antibiotics and anticancer agents. The modular genetic architecture of these...
- 19From: Nature Reviews Microbiology. (Vol. 3, Issue 12) Peer-ReviewedAuthor(s): Sheilagh Molloy Gram-positive microorganisms face a unique challenge when it comes to protein folding and secretion. Although all microorganisms lack the endoplasmic reticulum (ER) found in eukaryotes,...