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- Search Terms:ISSN: 15537366AndISSN: 15537374AndVolume Number: 3AndIssue Number: 12AndStart Page: e192AndDate: 2007 Revise Search
- 1From: PLoS Pathogens. (Vol. 3, Issue 12) Peer-ReviewedInactivation of host Rho GTPases is a widespread strategy employed by bacterial pathogens to manipulate mammalian cellular functions and avoid immune defenses. Some bacterial toxins mimic eukaryotic Rho...
- 2From: PLoS Pathogens. (Vol. 3, Issue 12) Peer-ReviewedA concept fundamental to viral pathogenesis is that infection induces specific changes within the host cell, within specific tissues, or within the entire animal. These changes are reflected in a cascade of altered...
- 3From: PLoS Pathogens. (Vol. 3, Issue 12) Peer-ReviewedThe type III secretion systems (TT55) encoded in Salmonella pathogenicity island-1 and -2 (SPI-1 and -2) are virulence factors required for specific phases of Salmonella infection in animal hosts. However, the host cell...
- 4From: PLoS Pathogens. (Vol. 3, Issue 12) Peer-ReviewedIn mammals, tissue-specific sets of pattern-recognition molecules, including Nod-like receptors (NLR), enable concomitant and sequential detection of microbial-associated molecular patterns from both the extracellular...
- 5From: PLoS Pathogens. (Vol. 3, Issue 12) Peer-ReviewedAccording to current models of retrovirus infection, receptor binding to the surface subunit (SU) of the envelope glycoprotein (Env) triggers a conformational change in the transmembrane subunit (TM) that mediates virus...
- 6From: PLoS Pathogens. (Vol. 3, Issue 12) Peer-ReviewedThe midgut environment of anopheline mosquitoes plays an important role in the development of the malaria parasite. Using genetic manipulation of anopheline mosquitoes to change the environment in the mosquito midgut...
- 7From: PLoS Pathogens. (Vol. 3, Issue 12) Peer-ReviewedLaboratory strains of the mouse Polyoma virus differ markedly in their abilities to replicate and induce tumors in newborn mice. Major determinants of pathogenicity lie in the sialic binding pocket of the major capsid...
- 8From: PLoS Pathogens. (Vol. 3, Issue 12) Peer-ReviewedTRIM5[alpha] is a restriction factor that limits infection of human cells by so-called N- but not B- or NB-tropic strains of murine leukemia virus (MLV). Here, we performed a mutation-based functional analysis of...
- 9From: PLoS Pathogens. (Vol. 3, Issue 12) Peer-ReviewedTRIM5[alpha] provides a cytoplasmic block to retroviral infection, and orthologs encoded by some primates are active against . Here, we present an evolutionary comparison of the TRIMS gene to its closest human paralogs:...
- 10From: PLoS Pathogens. (Vol. 3, Issue 12) Peer-ReviewedIt is well documented that the density of Plasmodium in its vertebrate host modulates the physiological response induced; this in turn regulates parasite survival and transmission. It is less clear that parasite density...