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- Search Terms:ISSN: 1553734XAndISSN: 15537358AndVolume Number: 3AndIssue Number: 12AndStart Page: e252AndDate: 2007 Revise Search
- 1From: PLoS Computational Biology. (Vol. 3, Issue 12) Peer-ReviewedComputational biology is an interdisciplinary science bred from fields as disparate as mathematics, chemistry, statistics, physics, biology, and computer science. Although the exact definition of computational biology...
- 2From: PLoS Computational Biology. (Vol. 3, Issue 12) Peer-ReviewedAcquisition of partially protective immunity is a dominant feature of the epidemiology of malaria among exposed individuals. The processes that determine the acquisition of immunity to clinical disease and to...
- 3From: PLoS Computational Biology. (Vol. 3, Issue 12) Peer-ReviewedProbabilistic graphical models (PGMs) have become a popular tool for computational analysis of biological data in a variety of domains. But, what exactly are they and how do they work? How can we use PGMs to discover...
- 4From: PLoS Computational Biology. (Vol. 3, Issue 12) Peer-ReviewedThe translation efficiency of most Saccharomyces cerevisiae genes remains fairly constant across poor and rich growth media. This observation has led us to revisit the available data and to examine the potential utility...
- 5From: PLoS Computational Biology. (Vol. 3, Issue 12) Peer-ReviewedOne of the major goals of comparative genomics is to understand the evolutionary history of each nucleotide in the human genome sequence, and the degree to which it is under selective pressure. Ascertainment of...
- 6From: PLoS Computational Biology. (Vol. 3, Issue 12) Peer-ReviewedRecent advances in single-neuron biophysics have enhanced our understanding of information processing on the cellular level, but how the detailed properties of individual neurons give rise to large-scale behavior...
- 7From: PLoS Computational Biology. (Vol. 3, Issue 12) Peer-ReviewedIn the presence of exogenous mortality risks, future reproduction by an individual is worth less than present reproduction to its fitness. Senescent aging thus results inevitably from transferring net fertility into...
- 8From: PLoS Computational Biology. (Vol. 3, Issue 12) Peer-ReviewedSwarming, a collective motion of many thousands of cells, produces colonies that rapidly spread over surfaces. In this paper, we introduce a cell-based model to study how interactions between neighboring cells...
- 9From: PLoS Computational Biology. (Vol. 3, Issue 12) Peer-ReviewedThe relationships between neural activity at the single-cell and the population levels are of central importance for understanding neural codes. In many sensory systems, collective behaviors in large cell groups can be...
- 10From: PLoS Computational Biology. (Vol. 3, Issue 12) Peer-ReviewedA ubiquitous building block of signaling pathways is a cycle of covalent modification (e.g., phosphorylation and dephosphorylation in MAPK cascades). Our paper explores the kind of information processing and filtering...