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- Search Terms:ISSN: 15491277AndISSN: 15491676AndVolume Number: 3AndIssue Number: 12AndStart Page: e487AndDate: 2006 Revise Search
- 1From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedIn 1993 the journal Pediatrics published an editorial entitled "TV or not TV: Fat is the question" [1]. It critiqued a study that used both cross-sectional and longitudinal analyses to ask whether after-school TV viewing...
- 2From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedABSTRACT Background Genetic and biochemical studies have indicated an important role for lipid metabolism in human longevity. Ashkenazi Jewish centenarians and their offspring have large low-density lipoprotein (LDL)...
- 3From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedThere has been growing recognition in the international community that health should be considered a human right, a right enshrined by several international treaties. Much less attention has been paid, however, to the...
- 4From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedABSTRACT Background Lung cancer is the leading cause of cancer-related death in the United States. Nearly 50% of patients with stages I and II non-small cell lung cancer (NSCLC) will die from recurrent disease...
- 5From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedABSTRACT Background With strict adherence to international recommended treatment guidelines, the case fatality for severe malnutrition ought to be less than 5%. In African hospitals, fatality rates of 20% are common...
- 6From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedABSTRACT Background Antibodies specifically affect the amygdala in a mouse model of systemic lupus erythematosus (SLE). The aim of our study was to investigate whether there is also specific involvement of the...
- 7From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedRecent global estimates of the number of blind people put the total at 37-42 million [1,2]. This figure is predicted to rise to over 75 million by the year 2020 as a result of increases in world population and life...
- 8From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedABSTRACT Background Blindness and low vision are thought to be common in southern Sudan. However, the magnitude and geographical distribution are largely unknown. We aimed to estimate the prevalence of blindness and...
- 9From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedABSTRACT Background Consistent with observational studies, a randomized controlled intervention trial of adult male circumcision (MC) conducted in the general population in Orange Farm (OF) (Gauteng Province, South...
- 10From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedThis month's PLoS Medicine publishes a paper describing the results of a very early drug discovery study. The nature of early drug development is to identify many promising compounds, only a small number of which...
- 11From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedDESCRIPTION of CASE A 35-year-old unemployed man presented to Accident and Emergency with a three-day history of progressive diplopia and a one-day history of slurred speech. There was no history of fever,...
- 12From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedABSTRACT Background The global spread of multidrug-resistant malaria parasites has led to an urgent need for new chemotherapeutic agents. Drug discovery is primarily directed to the asexual blood stages, and few...
- 13From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedThe Problem: Sharp Increase in Syphilis among Men Who Have Sex with Men San Francisco experienced a sharp rise in early syphilis between 1999 and 2002, with the number of cases rising from 44 to 494 per year (Figure...
- 14From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedABSTRACT Background Hepatitis C virus (HCV)-specific T cell responses are critical for spontaneous resolution of HCV viremia. Here we examined the effect of a lymphotropic virus, HIV-1, on the ability of coinfected...
- 15From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedIn allocating public health resources, the guiding principle should be an evidence-based quantification of need. A significant effort to categorize diseases by their global morbidity and mortality impact has developed...
- 16From: PLoS Medicine. (Vol. 3, Issue 12) Peer-Reviewed
Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection.
ABSTRACT Background During acute and early HIV-1 infection (AEI), up to 60% of CD[4.sup.+] T cells in the lamina propria of the lower gastrointestinal (GI) tract are lost as early as 2-4 wk after infection.... - 17From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedABSTRACT Background TV viewing has been linked to metabolic-risk factors in youth. However, it is unclear whether this association is independent of physical activity (PA) and obesity. Methods and Findings We did...
- 18From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedABSTRACT Background Inappropriate activation of the renin-angiotensin system may play a part in the development of preeclampsia. An insertion/deletion polymorphism within the angiotensin-I converting enzyme gene...
- 19From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedHeated debates and controversies surrounding the regulation of medical residents' work hours have raged for over twenty years. In the wake of Libby Zion's untimely death in 1984 and resulting recommendations by the Bell...
- 20From: PLoS Medicine. (Vol. 3, Issue 12) Peer-ReviewedABSTRACT Background Trachoma is a leading cause of preventable blindness. Reports from eye surgery camps and anecdotal data indicated that blinding trachoma is a serious cause of visual impairment in Mankien payam...