Showing Results for
- Academic Journals (15)
Search Results
- 15
Academic Journals
- 15
- Search Terms:
- 1From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedStroke, a major cause of disability and mortality in the elderly, occurs when a cerebral blood vessel is occluded or ruptured, resulting in ischemic damage and death of brain cells. The injury mechanism involves...
- 2From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedDespite extensive research efforts in the field of cerebral ischemia, numerous disappointments came from the translational step. Even if experimental studies showed a large number of promising drugs, most of them failed...
- 3From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedBackground After promising results in experimental stroke, normobaric (NBO) or hyperbaric oxygenation (HBO) have recently been discussed as co-medication with tissue plasminogen activator (tPA) for improving outcome....
- 4From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedBackground ATP-binding cassette transporters at the blood-brain barrier are actively regulated upon ischemic stroke in a way that impedes the access of pharmacological compounds to the brain tissue. The luminal...
- 5From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedSimultaneous color contrast and color constancy are memory processes associated with color vision, however, the gender-related differences of 'physiologic color space' remains unknown. Color processing was studied in 16...
- 6From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedThe investigation of central nervous system vascular changes in the pathophysiology of multiple sclerosis (MS) is a time-honored concept. Yet, recent reports on changes in venous cerebrospinal outflow, the advent of new...
- 7From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedIn the era of evidence-based medicine, large, randomized, controlled, multicenter studies represent the "summit of evidence". In contrast to specialties like cardiology, the majority of randomized, controlled trials in...
- 8From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedBackground Platelets play an important role in ischemic stroke. GPIb[alpha] is a major platelet receptor that is critical for platelet adhesion to exposed subendothelial matrix components at sites of vascular damage....
- 9From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedBackground Intra-arterial (IA) administration of rt-PA for ischemic stroke has the potential for greater thrombolytic efficacy, especially for a large thrombus in the M1 or M2 segment of the middle cerebral artery...
- 10From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedBackground This study was undertaken to test the hypothesis that a combination of excitatory anodal transcranial direct current stimulation (tDCS) to the contralateral motor cortex and inhibitory cathodal tDCS to the...
- 11From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedAuthors: Tim Magnus (corresponding author) [1]; Ralf A Linker (corresponding author) [2]; Sven G Meuth (corresponding author) [3]; Christoph Kleinschnitz (corresponding author) [4]; Thomas Korn (corresponding author)...
- 12From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedBackground Angiotensin II type 1 receptor (AT1R) blockers lower the incidence of ischemic stroke in hypertensive patients and attenuate brain inflammation and injury in animal models. Although AT1R on both blood...
- 13From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedBackground To date, recombinant tissue plasminogen activator (rtPA) is the only approved drug for ischemic stroke. It is intravenously administered functioning as a thrombolytic agent and is used to obtain...
- 14From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedBackground FTY720, an immunomodulator derived from a fungal metabolite which reduces circulating lymphocyte counts by increasing the homing of lymphocytes to the lymph nodes has recently gained interest in stroke...
- 15From: Experimental & Translational Stroke Medicine. (Vol. 3) Peer-ReviewedBackground Inflammatory cascades contribute to secondary injury after intracerebral hemorrhage (ICH) via humoral factors and cell-mediated cytotoxicity. Several experimental models were previously developed to...