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- 1From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedAuthor(s): Stefan M Woerner [1]; Matthias Kloor [1]; Annegret Mueller [2]; Josef Rueschoff [3]; Nicolaus Friedrichs [4]; Reinhard Buettner [4]; Moriz Buzello [5]; Peter Kienle [6]; Hanns-Peter Knaebel [6]; Erdmute...
- 2From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedAuthor(s): Thomas R Berton [1]; David L Mitchell [1]; Ruifeng Guo [1]; David G Johnson [1] The E2F family of transcription factors regulates the expression of genes involved in proliferation, apoptosis and DNA repair...
- 3From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedAuthor(s): Sue Ok Kim [1]; Joydeb Kumar Kundu [1]; Young Kee Shin [1]; Jin-Hong Park [2]; Myung-Haing Cho [2]; Tae-Yoon Kim [3]; Young-Joon Surh [1] Multiple lines of evidence suggest that inflammation is causally...
- 4From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedAuthor(s): S Park [1]; C D James [1, 2] Gene amplification is a mechanism for increasing gene copy number, and is observed in nearly all types of solid tumors (Schwab, 1999). Proteins encoded by amplified genes are...
- 5From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedAuthor(s): Serena Vannucchi [1]; Maria V Chiantore [1]; Gianna Fiorucci [1, 2]; Zulema A Percario [3]; Stefano Leone [3]; Elisabetta Affabris [3]; Giovanna Romeo [1, 2] There is accumulating evidence that cell cycle...
- 6From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedAuthor(s): Tina Mukherjee [1]; James Castelli-Gair HombrÃa [2, 3]; Martin P Zeidler [1] The JAK/STAT signal transduction cascade was first identified because of its role in the transduction of interferon, cytokine and...
- 7From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedAuthor(s): Christine Siligan [1]; Jozef Ban [1]; Radostina Bachmaier [1]; Laura Spahn [1]; Michael Kreppel [1]; Karl-Ludwig Schaefer [2]; Christopher Poremba [2]; Dave N T Aryee [1]; Heinrich Kovar [1] Ewing's sarcoma...
- 8From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedAuthor(s): Valérie Soenen-Cornu [1, 2]; Cristina Tourino [3]; Marie-Laure Bonnet [4]; Martine Guillier [4]; Stéphane Flamant [3, 4]; Rami Kotb [5]; Alain Bernheim [6]; Jean-Henri Bourhis [5]; Claude Preudhomme [1, 2];...
- 9From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedAuthor(s): Michela Mattioli [1]; Luca Agnelli [1]; Sonia Fabris [1]; Luca Baldini [1]; Fortunato Morabito [2]; Silvio Bicciato [3]; Donata Verdelli [1]; Daniela Intini [1]; Lucia Nobili [1]; Lilla Cro [1]; Giancarlo...
- 10From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedThe c-Abl and Arg nonreceptor tyrosine kinases are activated in the response of cells to oxidative stress. The present studies demonstrate that treatment of cells with 0.1 mM H[sub.2]O[sub.2] is associated with...
- 11From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedTransformation of chick embryo fibroblasts (CEFs) by the v-Jun oncoprotein correlates with a downregulation of the alpha 2 (I) collagen gene. To investigate whether this gene constitutes a direct target of v-Jun, an...
- 12From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedRetinoic acid (RA) arrests the growth of EBV-immortalized lymphoblastoid B cell lines (LCLs) by upregulating the cyclin-dependent kinase inhibitor p27[sup.Kip1]. Here, we show that in LCLs, RA inhibits ubiquitination...
- 13From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedThe E5 protein of human papillomavirus type 16 (HPV16) is a small hydrophobic protein, which localizes to the cell membrane, Golgi apparatus and endosomes. HPV16 E5 enhances the activation of the epidermal growth factor...
- 14From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedBoth human and murine ARF proteins have been recently reported to impair rRNA maturation and ribosomes biogenesis through a p53-independent pathway. A specific interaction has been established between 5.8S rRNA and the...
- 15From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedMdm2 and MdmX function as cellular regulators of the p53 tumor suppressor protein. Intriguingly, the activities of these proteins are interdependent; MdmX stabilizes Mdm2, enabling its activities towards p53, but it...
- 16From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedResistance to antiandrogen therapy in patients with metastatic prostate cancer poses a major challenge, which, if overcome, may lead to significant advances in the treatment of these patients. Hormone resistance of...
- 17From: Oncogene. (Vol. 24, Issue 15) Peer-ReviewedAlterations in migration and adhesion are critical to invasion and metastasis. To examine signaling pathways important for colon tumor metastasis, cells of increased migratory potential from the low migratory SW480...