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- 1From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedAuthor(s): Masaki Kamio [1, 2]; Takafumi Yoshida [1]; Hisanobu Ogata [1]; Tsutomu Douchi [2]; Yukihiro Nagata [2]; Makoto Inoue [3]; Mamoru Hasegawa [3]; Yoshikazu Yonemitsu [4]; Akihiko Yoshimura [1] Suppressor of...
- 2From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedAuthor(s): Keiko Kobayashi [1, 2]; Michiho Nishioka [1]; Takashi Kohno [1]; Masaki Nakamoto [1]; Arafumi Maeshima [3]; Kazuhiko Aoyagi [4]; Hiroki Sasaki [4]; Seiichi Takenoshita [2]; Haruhiko Sugimura [5]; Jun Yokota...
- 3From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedAuthor(s): Ming-Shyue Lee [1]; Tsukasa Igawa [1]; Ming-Fong Lin [1, 2, 3] Androgens are required for the development and maintenance of both male phenotype and male reproductive organs, including the prostate (Kokontis...
- 4From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedAuthor(s): Torstein Baade Ro [1]; Randi Utne Holt [1]; Anne-Tove Brenne [1]; Henrik Hjorth-Hansen [2]; Anders Waage [1]; Oyvind Hjertner [2]; Anders Sundan [1]; Magne Borset [1] Multiple myeloma is a B-lymphocyte...
- 5From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedAuthor(s): Frédérique Deshayes [1]; Geneviève Laprée [1]; Alain Portier [1]; Yolande Richard [1]; Philippe Pencalet [2]; Dominique Mahieu-Caputo [3]; Philippe Horellou [3]; Andréas Tsapis [1] Tumour necrosis...
- 6From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedAuthor(s): Lijian Hui [1]; Xin Zhang [2]; Xin Wu [3]; Zhixin Lin [4]; Qingkang Wang [2]; Yixue Li [5]; Gengxi Hu [1] One of the remarkable revelations that the recent description and annotation of the human genome from...
- 7From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedAuthor(s): Esra Toussaint-Smith [1]; David B Donner [1]; Ann Roman [1] Human papillomaviruses (HPVs) are small double-stranded DNA viruses that infect keratinocytes, causing a wide range of hyperproliferative diseases....
- 8From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedAuthor(s): Simon C Gamble [1]; Michael Odontiadis [1]; Jonathan Waxman [1]; Jules A Westbrook [2]; Michael J Dunn [3]; Robin Wait [4]; Eric W-F Lam [1]; Charlotte L Bevan [1] Prostate cancer is now the most commonly...
- 9From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedGenotoxic carcinogens exert their tumorigenic effects in part by inducing genomic instability. We recently showed that loss of heterozygosity (LOH) on chromosome 12 associates significantly with the induction of...
- 10From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedRRR-[alpha]-tocopheryl succinate ([alpha]-vitamin E succinate, VES), one of the vitamin E derivatives, can effectively inhibit the proliferation of human prostate cancer cells. However, little is known about its effect...
- 11From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedPIASy, a member of the protein inhibitor of activated STAT (PIAS) family, represses the transcriptional activity of the androgen receptor (AR). In this report, we investigate the mechanism of PIASy-mediated repression...
- 12From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedThe ATM kinase is a tumour suppressor and a key activator of genome integrity checkpoints in mammalian cells exposed to ionizing radiation (IR) and other insults that elicit DNA double-strand breaks (DSBs). In response...
- 13From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedThe chicken c-mil/raf-1 gene (formerly also known as c-mht) was originally identified in the search for the cellular counterpart to the v-mil oncogene of the Mill Hill 2 retrovirus and was among the first cellular...
- 14From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedThe transcription factors STAT5A and STAT5B (STAT: signal transducer and activator of transcription) play a major role in the signaling events elicited by a number of growth factor and cytokine receptors. In this work,...
- 15From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedExogenous expression of the catalytic subunit of telomerase, hTERT, in a normal human foreskin fibroblast cell strain resulted in telomerase activity and an extended proliferative lifespan prior to a period of crisis....
- 16From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedThe drs gene was originally isolated as a suppressor against v-src transformation. Expression of drs mRNA was markedly downregulated in a variety of human cancer cell lines and tissues, suggesting that the drs gene acts...
- 17From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedThe Wilms' tumour suppressor gene, WT1, encodes a zinc-finger protein that is mutated in Wilms' tumours and other malignancies. WT1 is one of the earliest genes expressed during kidney development. WT1 proteins can...
- 18From: Oncogene. (Vol. 23, Issue 17) Peer-ReviewedThe HR6A and HR6B genes, homologs of the yeast RAD6 gene, encode ubiquitin conjugating enzymes that are required for postreplication repair (PRR) of DNA and damage-induced mutagenesis. We show here that consistent with...