Showing Results for
- Academic Journals (14)
Search Results
- 14
Academic Journals
- 14
- Search Terms:
- 1From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedBackground Ethanol has been shown to stimulate the beat frequency of respiratory cilia at concentrations encountered during social drinking, while one of its metabolites, acetaldehyde, has been shown to cause a...
- 2From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedDysfunctional cilia underlie a broad range of cellular and tissue phenotypes and can eventually result in the development of ciliopathies: pathologically diverse diseases that range from clinically mild to highly...
- 3From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedBackground The primary cilium coordinates signalling in development, health and disease. Previously we have shown that the cilium is essential for the anabolic response to loading and the inflammatory response to...
- 4From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedBackground Lower airway abnormalities are common in patients with primary ciliary dyskinesia (PCD), a pediatric syndrome that results from structural or functional defects in motile cilia. Patients can suffer from...
- 5From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedBackground Cilia are small, microtubule-based protrusions important for development and homeostasis. We recently demonstrated that the planar cell polarity effector protein Fuz is a critical regulator of axonemal...
- 6From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedIntraflagellar transport (IFT) is required for the assembly and maintenance of cilia, as well as the proper function of ciliary motility and signaling. IFT is powered by molecular motors that move along the axonemal...
- 7From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedBackground The building of a cilium or flagellum requires molecular motors and associated proteins that allow the relocation of proteins from the cell body to the distal end and the return of proteins to the cell...
- 8From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedBackground Cilia are found on nearly every cell type in the mammalian body, and have been historically classified as either motile or immotile. Motile cilia are important for fluid and cellular movement; however, the...
- 9From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedCilia and flagella perform diverse roles in motility and sensory perception, and defects in their construction or their function are responsible for human genetic diseases termed ciliopathies. Cilia and flagella...
- 10From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedBackground Most motile cilia and flagella have nine outer doublet and two central pair (CP) microtubules. Outer doublet microtubules are continuous with the triplet microtubules of the basal body, are templated by...
- 11From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedBackground Cilia are essential organelles in multiple organ systems, including the kidney where they serve as important regulators of renal homeostasis. Renal nephron cilia emanate from the apical membrane of...
- 12From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedAs an organelle, the cilium contains a unique complement of protein and lipid. Recent work has begun to shed light on the mechanisms that regulate entry of ciliary proteins into the compartment. Here, we focus on the...
- 13From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedPrimary cilia have been previously linked to the central regulation of satiety. Thetubby mouse is characterized by maturity-onset obesity and blindness. Arecent paper demonstrates molecular defects in trafficking of...
- 14From: Cilia. (Vol. 2, Issue 1) Peer-ReviewedBackground Circulation of cerebrospinal fluid (CSF) through the ventricular system is driven by motile cilia on ependymal cells of the brain. Disturbed ciliary motility induces the formation of hydrocephalus, a...