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- 1From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Joseph F Ryan [1]; Andreas D Baxevanis (corresponding author) [1] Background The thirty-plus metazoan phyla are each characterized by a distinct "Bauplan" (or body plan; see [1, 2]). A major challenge facing...
- 2From: Biology Direct. (Vol. 2) Peer-Reviewed
nuID: a universal naming scheme of oligonucleotides for Illumina, Affymetrix, and other microarrays.
Authors: Pan Du [1]; Warren A Kibbe [1]; Simon M Lin (corresponding author) [1] Background Oligonucleotides (often simply referred to as oligos or oligomers) are typically between 25 to 75 bases long. Microarray... - 3From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Gelio Alves [1]; Aleksey Y Ogurtsov [1]; Wells W Wu [2]; Guanghui Wang [2]; Rong-Fong Shen [2]; Yi-Kuo Yu (corresponding author) [1] Introduction Mass spectrometry (MS) based protein identification plays a...
- 4From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Johannes WIM Simons (corresponding author) [1] Background The 'creation' of Dolly, the cloned sheep [1] has proved that it is possible to reprogram the nucleus of a somatic cell and has suggested that there...
- 5From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Artem S Novozhilov [1]; Yuri I Wolf [1]; Eugene V Koonin (corresponding author) [1] Background Arguably, one of the most profound, fundamental features of all life forms existing on earth is that, with...
- 6From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Alessandro Pintar (corresponding author) [1]; Alfredo De Biasio [1]; Matija Popovic [1]; Neli Ivanova [1]; Sándor Pongor [1] Background Notch-mediated signal transduction controls cell fate and is a key...
- 7From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Kira S Makarova [1]; Alexander V Sorokin [1]; Pavel S Novichkov [1]; Yuri I Wolf [1]; Eugene V Koonin (corresponding author) [1] Background A robust classification of genes based on accurately deciphered...
- 8From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Neil R Smalheiser (corresponding author) [1] Background The purpose of this paper is discuss the potential role of the endosome-derived vesicle known as the secretory exosome as a means of intercellular...
- 9From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Larry J Wilhelm [1]; H James Tripp [1]; Scott A Givan [2]; Daniel P Smith [1]; Stephen J Giovannoni (corresponding author) [1] Open peer review Reviewed by Eugene Koonin, Igor B. Jouline (Zhulin) and Peer...
- 10From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Galina Glazko [1,2]; Vladimir Makarenkov [3]; Jing Liu [1,4]; Arcady Mushegian (corresponding author) [1,5] Background The interest in bacteriophage biology may be at its all-time high, with the new...
- 11From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Fabrizio Lillo [1,2]; David C Krakauer (corresponding author) [1] Background One of the remarkable discoveries arising from the study of microbial genomes is that a single sequence of nucleic acid bases can...
- 12From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Michael R Rose (corresponding author) [1]; Todd H Oakley [2] Background The first two biological syntheses Biology has been re-integrated twice already, first by Darwin in 1859 and then during the "Modern...
- 13From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Lev Klebanov [1,2]; Andrei Yakovlev (corresponding author) [1,2] 1. Background It is widely believed that a high level of technical noise in microarray data is the most critical deterrent to the successful...
- 14From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Lev Klebanov [1,2]; Linlin Chen [1]; Andrei Yakovlev (corresponding author) [1] 1. Background Okoniewski and Miller [1] reported evidence they believe to be in favor of the idea that spurious positive...
- 15From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Gelio Alves [1]; Aleksey Y Ogurtsov [1]; Yi-Kuo Yu (corresponding author) [1] Open peer review Reviewed by Frank Eisenhaber, Wing-Cheong Wong (co-reviewer invited by Frank Eisenhaber), Dongxiao Zhu...
- 16From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Jittima Piriyapongsa [1]; Mark T Rutledge [1]; Sanil Patel [1]; Mark Borodovsky [1,2,3]; I King Jordan (corresponding author) [1] Background Transposable elements (TEs) are DNA sequences capable of moving...
- 17From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Georgii A Bazykin [1,2]; Fyodor A Kondrashov [3]; Michael Brudno [4]; Alexander Poliakov [5]; Inna Dubchak [5,6]; Alexey S Kondrashov (corresponding author) [7] Open peer review Reviewed by John McDonald...
- 18From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Albert DG de Roos (corresponding author) [1] Background The evolution of life and the origins of DNA and RNA as the carriers of information are still a mystery. It has been proposed that the DNA world was...
- 19From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: Jacob Bock Axelsen [1,2]; Koon-Kiu Yan [2,3]; Sergei Maslov (corresponding author) [2,3] Open peer review This article was reviewed by Eugene Koonin, Yuri Wolf (nominated by Eugene Koonin), David Krakauer,...
- 20From: Biology Direct. (Vol. 2) Peer-ReviewedAuthors: L Aravind (corresponding author) [1] Editorial Over two decades ago the first electronic databases which systematically collected protein and nucleic acid sequence and structure data came into existence....