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- 1From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedIn the version of this article initially published, the name of the antibody bapineuzumab was incorrectly spelled as 'bapineuzimab' throughout the text. The error has been corrected in the HTML and PDF versions of the...
- 2From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedVoters in the US state of Mississippi decided last month that an embryo should not be given the legal rights and privileges of living people--a proposal that could have wreaked havoc on reproductive therapy and stem...
- 3From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedAmyotrophic lateral sclerosis (ALS) is characterized by upper and lower motor neuron dysfunction and loss, rapidly progressive muscle weakness, wasting and death (1-3). Many factors, including mitochondrial dysfunction,...
- 4From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedThe discovery that skin cells from an adult human can be reprogrammed back to their embryonic stage and then differentiated to produce neuron-like cells in culture opens an opportunity to study disease pathogenesis and...
- 5From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedThe first results for the phase 3 RTS,S vaccine trial (1) confirm the results of phase 2 studies indicating that vaccinated individuals are afforded significant protection in the first few months after vaccination, but...
- 6From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedIn an effort to lessen Abbott Laboratories' reliance on Humira (adalimumab), a monoclonal antibody that accounts for about 20% of the company's $40 billion-a-year revenue, the Chicago-based drugmaker announced plans on...
- 7From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedCellular production of nitric oxide (NO) by nitric oxide synthase (NOS) in the face of limiting pools of arginine requires the intracellular citrulline-to-NO pathway, catalyzed by the enzyme argininosuccinate lyase...
- 8From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedBile acids are known to ward off fatty liver disease and maintain stable blood sugar levels. Thus, researchers have been on the lookout for ways to boost the production of these liver secretions. The liver receptor...
- 9From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedOsteoarthritis, characterized by the breakdown of articular cartilage in synovial joints, has long been viewed as the result of 'wear and tear' (1). Although low-grade inflammation is detected in osteoarthritis, its...
- 10From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedJanuary--The NCATS out of the bag: The US National Institutes of Health (NIH) moved quickly with its initial plan to create a new center for translational medicine, releasing a "straw model" on 16 January that showed...
- 11From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedMet is the transmembrane tyrosine kinase cell surface receptor for hepatocyte growth factor (HGF) and is structurally related to the insulin receptor (INSR) tyrosine kinase. Here we report that the HGF-Met axis...
- 12From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedThe Bleeding Disease: Hemophilia and the Unintended Consequences of Medical Progress Stephen Pemberton The Johns Hopkins University Press, 2011 400 pp., hardcover, $50.00 ISBN:1421401150 Few stories in modern...
- 13From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedThe approval this year of the first directacting antiviral drugs for the hepatitis C virus has ushered in a new era of treatment. Since the mid-May launch of Incivek (telaprevir) and Victrelis (boceprevir)--both of...
- 14From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedThe World Health Organization (WHO), responding to the strength of Swiss currency and a slimmed-down budget, announced plans last month to redistribute staff from its headquarters in Geneva to regional offices around...
- 15From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedRetracting a paper is perhaps the most unpleasant task a journal has to face, particularly if the retraction involves scientific misconduct. With the number of retractions on the rise, an improved mechanism to deal with...
- 16From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedTumor development often involves genomic changes that affect protein expression, so chromatin alterations have received a lot of attention as possible therapeutic targets. A handful of recent studies support this idea...
- 17From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedBreast cancer is a heterogeneous disease that has a wide range of molecular aberrations and clinical outcomes. Here we used paired-end transcriptome sequencing to explore the landscape of gene fusions in a panel of...
- 18From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedThe pharmaceutical industry, like almost every other industry these days, is looking to China for growth. Over the past few years, numerous foreign drug companies, including GlaxoSmithKline, Novartis, Pfizer and Sanofi,...
- 19From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedChemotherapy can save the lives of many individuals with cancer. Unfortunately, it usually causes infertility after treatment, posing a concern for these people who will face a lifetime condition that considerably...
- 20From: Nature Medicine. (Vol. 17, Issue 12) Peer-ReviewedIn the version of this article initially published, lanes from the original blot shown in Figure 2b (NIZ and IZ samples, blotting for 55-kDa Kir2.1 and GAPDH) were rearranged in the published figure. The two lanes at...