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- 1From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedLast month, Carolyn Bertozzi became the first woman to win the prestigious Massachusetts Institute of Technology (MIT)-Lemelson Prize, a $500,000 award that honors midcareer inventors. Bertozzi, a chemical biologist,...
- 2From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedCandida albicans is a major fungal pathogen that causes serious systemic and mucosal infections in immunocompromised individuals. In yeast, histone H3 Lys56 acetylation (H3K56ac) is an abundant modification regulated by...
- 3From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedFor many people tracking their family history, the Web offers a wealth of information to aid their genealogical search. And, for the medically inclined, some online discussion forums focus specifically on tracking...
- 4From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedBasic research on the mechanisms of blood coagulation and the inflammatory response during tissue damage has revealed new potential targets for antithrombotic drugs. In 'Bench to Bedside', Charles T. Esmon examines...
- 5From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedJun 8 Insulin-signaling deficiency is well known for its role in diabetes, but it may also be linked to schizophrenia. When researchers disrupted insulin signaling inside the neuron cells of mice, the mice showed...
- 6From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedJun 4 More than 100 individuals with Parkinson's disease filed a class-action lawsuit against Pfizer Australia and Aspen Pharmaceuticals, the makers of the drugs Cabaser and Permax, respectively. The litigants...
- 7From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedMay 20 A US congressional committee announced that it was opening an investigation into personal genomics companies. Chief executives from 23andMe, Pathway Genomics and Navigenics received letters requesting a wealth...
- 8From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedChromosomal translocations can promote cancers by eliciting the expression of fusion genes with oncogenic activity. The identification of translocations affecting RAF genes in prostate and gastric cancers and melanoma...
- 9From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedA macrophage-derived protein blocks the synthesis of new fatty acids to help break down fat droplets, new research shows (Cell Metab. 11, 479-492, 2010). Macrophages are known to infiltrate fat tissue, where they may...
- 10From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedA study in mice indicates that schizophrenia might involve defects in noradrenaline-mediated signaling, underscoring the potential of this neurotransmitter system as a therapeutic target (PLoS Biol. 8, e1000393)....
- 11From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedWith austerity measures tightening across Europe, and governments looking for quick cost-saving wins, drug prices have found themselves on the chopping board across the continent. But while politicians rejoice at having...
- 12From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedEver since Edward Jenner discovered the smallpox vaccine two centuries ago, immunization efforts have almost exclusively focused on activating the immune system. But when it comes to multiple sclerosis and other...
- 13From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedThe US Food and Drug Administration (FDA), generally a tightlipped agency, could be set for a change. The agency is proposing to release information that is currently kept behind a wall, such as when an application for...
- 14From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedOne of the major goals in thrombosis research is to identify agents that block thrombosis without increasing the risk of bleeding. Current therapies to prevent thrombosis target molecules that are also essential to...
- 15From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedMay 26 A review of 45 genome-wide association studies that identified cancer risk factors concluded that larger sample sizes are needed for such analyses. The authors said that the average identified risk factor for...
- 16From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedAn immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactions. Hitomi, K. et al. Nat. Immunol. 11, 601-607. An inhibitory receptor expressed by mast cells...
- 17From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedPregnancy increases the demand for insulin by various tissues in the body, a condition that can lead to gestational diabetes. To shield against this condition, insulin-producing beta cells proliferate in a process now...
- 18From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedDuring pregnancy, the energy requirements of the fetus impose changes in maternal metabolism. Increasing insulin resistance in the mother maintains nutrient flow to the growing fetus, whereas prolactin and placental...
- 19From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedLast month, San Francisco officials granted a city proclamation to Gero Hutter for his 2007 discovery that a bone marrow transplant could, it seems, cure a person of HIV. The German hematologist's findings raised hopes...
- 20From: Nature Medicine. (Vol. 16, Issue 7) Peer-ReviewedJun 3 City officials in Cambridge, Massachusetts signed off on the development of a $1 billion biotechnology complex. The 'Binney Street Project' will be located in the heart of Kendall Square, already home to the...