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- 1From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedWhen we recognize a sensory event, we experience a confident feeling that we certainly know the perceived world 'here and now'. However, it is unknown how and where the brain generates such 'perceptual confidence'. Here...
- 2From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedTwo studies in this issue report the discovery of different types of uncertainty signals in little-studied, but critical, regions of the forebrain: decision confidence in the pulvinar and reward risk in the anterodorsal...
- 3From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedIntrahippocampal transplantation of inhibitory interneuron progenitors derived from the medial ganglionic eminence markedly ameliorates the seizure activity and neurobehavioral deficits typically observed in the...
- 4From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedDifferent visual features of an object, such as its position and direction of motion, are important elements for animal orientation, but the neural circuits extracting them are generally not well understood. We analyzed...
- 5From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedFragile X syndrome is caused by the loss of Fragile X mental retardation protein (FMRP), an RNA-binding protein that suppresses protein translation. We found that FMRP binds to Down syndrome cell adhesion molecule...
- 6From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedNatural environments are uncertain. Uncertainty of emotional outcomes can induce anxiety and raise vigilance, promote and signal the opportunity for learning, modulate economic choice and regulate risk-seeking. Here we...
- 7From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedLittle is known about how attention changes the cortical representation of sensory information in humans. On the basis of neurophysiological evidence, we hypothesized that attention causes tuning changes to expand the...
- 8From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedScientists are no strangers to the intimidation tactics employed by animal rights activists. Despite the rise of pro-animal testing movements, such as Pro-test (http://www.pro-test.org.uk/), animal rights extremism is...
- 9From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedNeural circuit assembly requires precise dendrite and axon targeting. We identified an evolutionarily conserved endoplasmic reticulum (ER) protein, Meigo, from a mosaic genetic screen in Drosophila melanogaster. Meigo...
- 10From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedImpaired GABA-mediated neurotransmission has been implicated in many neurologic diseases, including epilepsy, intellectual disability and psychiatric disorders. We found that inhibitory neuron transplantation into the...
- 11From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedHigh-level cortical systems for spatial navigation, including entorhinal grid cells, critically depend on input from the head direction system. We examined spiking rhythms and modes of synchrony between neurons...
- 12From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedThe adult CNS contains an abundant population of oligodendrocyte precursor cells ([NG2.sup.+] cells) that generate oligodendrocytes and repair myelin, but how these ubiquitous progenitors maintain their density is...
- 13From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedExcessive glucocorticoid exposure during chronic stress causes synapse loss and learning impairment. Under normal physiological conditions, glucocorticoid activity oscillates in synchrony with the circadian rhythm....
- 14From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedAlthough we know much about the capacity of neurons to integrate synaptic inputs in vitro, less is known about synaptic integration in vivo. Here we address this issue by investigating the integration of inputs from the...
- 15From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedStress impairs cognition via corticotropin-releasing hormone receptor 1 (CRHR1), but the molecular link between abnormal CRHR1 signaling and stress-induced cognitive impairments remains unclear. We investigated whether...
- 16From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedAnatomical studies have led to the assertion that intratelencephalic and pyramidal tract cortical neurons innervate different striatal projection neurons. To test this hypothesis, we measured the responses of mouse...
- 17From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedSensory systems exhibit mechanisms of neural adaptation, which adjust neuronal activity on the basis of recent stimulus history. In primary visual cortex (V1) in particular, adaptation controls the responsiveness of...
- 18From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedA study shows that circadian glucocorticoid oscillations have dual roles in dendritic spine plasticity, controlling spine formation and elimination through distinct mechanisms important for motor learning. Chronic...
- 19From: Nature Neuroscience. (Vol. 16, Issue 6) Peer-ReviewedA study reports that fixation and optomotor responses in Drosophila rely on parallel neural processing of position and motion information, but interact at the behavioral level. As we walk through our environment, our...