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- 1From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedAustralia's Open Pool Australian Lightwater (OPAL) research reactor has the potential to "make a real difference" in the effort to deal with the global shortage of radioactive isotopes used for medical research and...
- 2From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedObesity increases the risk of insulin resistance, but scientists haven't known exactly how. Seamus Crowe and Lindsay Wu et al. find a role for a protein known to be upregulated in people with the metabolic syndrome or...
- 3From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedInflammation is increasingly regarded as a key process underlying metabolic diseases in obese individuals. In particular, obese adipose tissue shows features characteristic of active local inflammation. At present,...
- 4From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedThe human stomach is one of the least hospitable environments on Earth. This dark, muscular cavity is filled with a noxious brew of hydrochloric acid and digestive enzymes designed to rip apart meat and potent enough to...
- 5From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedThe phase 2b trial of Merck's recombinant adenovirus type 5-based HIV-1 vaccine was halted as the vaccine seemed to have increased HIV-1 acquisition in vaccine recipients who had preexisting immunity to the adenovirus...
- 6From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedWhat are the most important questions that the HIV field needs to answer to make progress? Nature Medicine asked this question to a group of HIV researchers to identify some of the key roadblocks in HIV research....
- 7From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedMiura, K. et al. Nat. Biotechnol. published online, doi:10.1038/nbt.1554 (9 June). Neuronal precursor cells derived from induced pluripotent stem (iPS) cell lines were evaluated for their ability to form teratomas....
- 8From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedLast month, DNA sequencing in the UK got a boost with the launch of the Genome Analysis Centre (TGAC) in the eastern city of Norwich. The 13.5 million [pounds sterling] ($22 million) facility hosts biologists and...
- 9From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedThe immunologic basis for the potential enhanced HIV-1 acquisition in adenovirus serotype 5 (Ad5)-seropositive individuals who received the Merck recombinant Ad5 HIV-1 vaccine in the STEP study remains unclear. Here we...
- 10From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedThree recent studies (1,2,3) bolster the argument for initiating antiretroviral therapy for HIV infection earlier than previously thought. Such arguments have been brewing for a while now, say three experts. Diane...
- 11From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedWe asked a group of HIV experts to tell us what they believe are the most pressing questions for the field. Twenty-five experts told us what they thought and their answers revealed some of the most important scientific...
- 12From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedTwo reports show how to extend lifespan in monkeys and mice. In a 20-year study, Richard Weindruch and his colleagues (Science 325, 201) asked whether restricting caloric intake can extend lifespan in rhesus...
- 13From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedJun 12 A survey of more than 700 people revealed public ignorance of anatomy: when shown pictures of the human body, only 45% of respondents correctly identified the location of the heart, and nearly 70%...
- 14From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedObesity and its associated metabolic syndromes represent a growing global challenge, yet mechanistic understanding of this pathology and current therapeutics are unsatisfactory. We discovered that [CD4.sup.+] T...
- 15From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedImaging agents that enable direct visualization and quantification of apoptosis in vivo have great potential value for monitoring chemotherapeutic response as well as for early diagnosis and disease monitoring. We...
- 16From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedStem cell researchers have found a key regulator of primordial germ cells, the cells that give rise to eggs and sperm. This regulator, lin28, was also overexpressed in a variety of human tumors, including most germ cell...
- 17From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedMost existing viral vaccines generate antibodies that either block initial infection or help eradicate the virus before it can cause disease. For HIV-1, obstacles to eliciting protective neutralizing antibodies MAW have...
- 18From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedWould you entrust your brain to a bank? Well, many people do after they die, and such brain banks--often funded by government agencies or disease charities--are essential for neuroscience research. They collect and...
- 19From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedJust over a year ago, advocates celebrated the signing of a landmark piece of legislation barring health insurers and employers from discriminating against people on the basis of their genetic information. The...
- 20From: Nature Medicine. (Vol. 15, Issue 8) Peer-ReviewedResearchers have identified a regulator of food intake that directly controls levels of a key appetite-quelling hormone. The regulator, prolylcarboxypeptidase (PRCP), degrades [alpha]-melanocyte-stimulating hormone...