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- 1From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedTranscription of immediate early genes (IEGs) in neurons is highly sensitive to neuronal activity, but the mechanism underlying these early transcription events is largely unknown. We found that several IEGs, such as...
- 2From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedAversive olfactory memory is formed in the mushroom bodies in Drosophila melanogaster. Memory retrieval requires mushroom body output, but the manner in which a memory trace in the mushroom body drives conditioned...
- 3From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedThe relationship between top-down enhancement and suppression of sensory cortical activity and large-scale neural networks remains unclear. Functional connectivity analysis of human functional magnetic resonance imaging...
- 4From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedIonotropic glutamate receptors principally mediate fast excitatory transmission in the brain. Among the three classes of ionotropic glutamate receptors, kainate receptors (KARs) have a unique brain distribution, which...
- 5From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedThe beautiful, undulating orientation maps in visual cortex have motivated many developmental models. A new study finds that this functional organization could be seeded in the retina by moire interference between...
- 6From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedMounting evidence suggests that understanding how the brain encodes information and performs computations will require studying the correlations between neurons. The recent advent of recording techniques such as...
- 7From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedLittle is known about which ion channels determine the resting electrical properties of presynaptic membranes. In recordings made from the rat calyx of Held, a giant mammalian terminal, we found resting potential to be...
- 8From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedTumor necrosis factor-[alpha]-converting enzyme (TACE; also known as ADAM17) is a proteolytic sheddase that is responsible for the cleavage of several membrane-bound molecules. We report that TACE cleaves neuregulin-1...
- 9From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedWe found that glia secrete myoglianin, a TGF-[beta] ligand, to instruct developmental neural remodeling in Drosophila. Glial myoglianin upregulated neuronal expression of an ecdysone nuclear receptor that triggered...
- 10From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedHow animals maintain proper amounts of sleep yet remain flexible to changes in environmental conditions remains unknown. We found that environmental light suppressed the wake-promoting effects of dopamine in fly brains....
- 11From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedThe orientation map is a hallmark of primary visual cortex in higher mammals. It is not yet known how orientation maps develop, what function they have in visual processing and why some species lack them. Here we...
- 12From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedWhen two socially naive Drosophila males meet, they will fight. However, prior social grouping of males reduces their aggression. We found olfactory communication to be important for modulating Drosophila aggression....
- 13From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedA study now shows that association of kainate receptors with the auxiliary protein Netol confers the slow activation and deactivation kinetics of synaptic responses, as well as the high agonist affinity seen in vivo....
- 14From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedAlthough individual nerve terminals from the same neuron often differ in neurotransmitter release characteristics, the extent to which endocytic retrieval of synaptic vesicle components differs is unknown. We used...
- 15From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedAlthough clathrin-mediated endocytosis is thought to be the predominant mechanism of synaptic vesicle recycling, it seems to be too slow for fast recycling. Therefore, it was suggested that a presorted and preassembled...
- 16From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedA new study used several mouse mutants to study insulin receptor function specifically in the ventromedial nucleus of the hypothalamus (VMH), and found a role for VMH insulin signaling in promoting high-fat diet-induced...
- 17From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedSteroidogenic factor 1 (SF-1)-expressing neurons of the ventromedial hypothalamus (VMH) control energy homeostasis, but the role of insulin action in these cells remains undefined. We show that insulin activates...
- 18From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedStriatal spiny neurons (SPNs) associate a diverse array of cortically processed information to regulate action selection. But how this is done by SPNs is poorly understood. A key step in this process is the transition...
- 19From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedDeciding when to leave a depleting resource to exploit another is a fundamental problem for all decision makers. The neuronal mechanisms mediating patch-leaving decisions remain unknown. We found that neurons in primate...
- 20From: Nature Neuroscience. (Vol. 14, Issue 7) Peer-ReviewedHumans are good at performing visual tasks, but experimental measurements have revealed substantial biases in the perception of basic visual attributes. An appealing hypothesis is that these biases arise through a...